Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …

The Amazonian rainforest is arguably the most species-rich terrestrial ecosystem in the
world, yet the timing of the origin and evolutionary causes of this diversity are a matter of …

▪ Abstract Research on human aggression has progressed to a point at which a unifying
framework is needed. Major domain-limited theories of aggression include cognitive …

In 1988, a British mountain climber named Jo Simpson wrote a book called Touching the
Void, a harrowing account of near death in the Peruvian Andes. It got good reviews, but, only …

Crohn's disease and ulcerative colitis, the two common forms of inflammatory bowel disease
(IBD), affect over 2.5 million people of European ancestry, with rising prevalence in other …

Background Whether the treatment of patients with hypertension who are 80 years of age or
older is beneficial is unclear. It has been suggested that antihypertensive therapy may …

We undertook a meta-analysis of six Crohn's disease genome-wide association studies
(GWAS) comprising 6,333 affected individuals (cases) and 15,056 controls and followed up …

Several risk factors for Crohn's disease have been identified in recent genome-wide
association studies. To advance gene discovery further, we combined data from three …

The ATM protein, encoded by the gene responsible for the human genetic disorder ataxia
telangiectasia (AT), regulates several cellular responses to DNA breaks. ATM shares a …

Background Endovascular therapy is increasingly used after the administration of
intravenous tissue plasminogen activator (t-PA) for patients with moderate-to-severe acute …