Cloning of a gene highly overexpressed in cancer coding for a novel KH-domain containing protein

F Müeller-Pillasch, U Lacher, C Wallrapp, A Micha… - Oncogene, 1997 - nature.com
In a previous large scale screen for differentially expressed genes in pancreatic cancer, we
identified a gene highly overexpressed in cancer encoding a novel protein with four K …

[HTML][HTML] Expression of the highly conserved RNA binding protein KOC in embryogenesis

…, B Pohl, M Wilda, U Lacher, M Beil, C Wallrapp… - Mechanisms of …, 1999 - Elsevier
The human KOC gene which is highly expressed in cancer shows typical structural features
of an RNA binding protein. We analyzed the temporal and spatial expression pattern of KOC …

A Novel Transmembrane Serine Protease (TMPRSS3) Overexpressed in Pancreatic Cancer1,2

C Wallrapp, S Hähnel, F Müller-Pillasch… - Cancer research, 2000 - AACR
We report the characterization of a novel serine protease of the chymotrypsin family, recently
isolated by cDNA-representational difference analysis, as a gene overexpressed in …

Use of encapsulated stem cells to overcome the bottleneck of cell availability for cell therapy approaches

…, PP Pino-Grace, S Pohl, C Weber, C Wallrapp… - Transfusion Medicine …, 2010 - karger.com
Nowadays cell-based therapy is rarely in clinical practice because of the limited availability
of appropriate cells. To apply cells therapeutically, they must not cause any immune …

Production process for stem cell based therapeutic implants: expansion of the production cell line and cultivation of encapsulated cells

…, P Pino-Grace, D Freimark, C Wallrapp… - Bioreactor Systems for …, 2010 - Springer
Cell based therapy promises the treatment of many diseases like diabetes mellitus,
Parkinson disease or stroke. Microencapsulation of the cells protects them against host-vs …

Cerebral transplantation of encapsulated mesenchymal stem cells improves cellular pathology after experimental traumatic brain injury

AMB Heile, C Wallrapp, PM Klinge, A Samii… - Neuroscience …, 2009 - Elsevier
Purpose:“Naked” human mesenchymal stem cells (MSC) are neuro-protective in
experimental brain injury (TBI). In a controlled cortical impact (CCI) rat model, we …

[HTML][HTML] Characterisation of physico-mechanical properties and degradation potential of calcium alginate beads for use in embolisation

REJ Forster, F Thürmer, C Wallrapp, AW Lloyd… - Journal of Materials …, 2010 - Springer
High molecular weight alginate beads with 59% mannuronic acid content or 68% guluronic
acid were prepared using a droplet generator and crosslinked in calcium chloride. The …

Characterization of a High Copy Number Amplification at 6q24 in Pancreatic Cancer Identifies c-myb as a Candidate Oncogene

C Wallrapp, F Müller-Pillasch, S Solinas-Toldo… - Cancer research, 1997 - AACR
In a recent study designed to identify chromosomal aberrations in pancreatic cancer tissues
using comparative genomic hybridization, a high copy number amplification on 6q was …

Expansion of human mesenchymal stem cells in a fixed-bed bioreactor system based on non-porous glass carrier–part A: inoculation, cultivation, and cell harvest …

…, P Pino-Grace, S Pohl, C Wallrapp… - … journal of artificial …, 2010 - journals.sagepub.com
Human mesenchymal stem cells (hMSC) are a promising cell source for several applications
of regenerative medicine. The cells employed are either autologous or allogenic; by using …

Perivascular delivery of encapsulated mesenchymal stem cells improves postischemic angiogenesis via paracrine activation of VEGF-A

…, R Holden, M Meloni, C Reni, C Wallrapp… - … , and vascular biology, 2013 - Am Heart Assoc
Objective—To test the therapeutic activity of perivascular transplantation of encapsulated
human mesenchymal stem cells (MSCs) in an immunocompetent mouse model of limb …