[HTML][HTML] Hypertension and chronic ethanol consumption: what do we know after a century of study?
KC Marchi, JJ Muniz, CR Tirapelli - World journal of cardiology, 2014 - ncbi.nlm.nih.gov
The influences of life habits on the cardiovascular system may have important implications
for public health, as cardiovascular diseases are among the leading causes of shorter life …
for public health, as cardiovascular diseases are among the leading causes of shorter life …
Effects of melatonin on thymic and oxidative stress dysfunctions during Trypanosoma cruzi infection
V Brazão, RP Colato, FH Santello… - Journal of Pineal …, 2018 - Wiley Online Library
Although the exact etiology of Chagas disease is not completely elucidated, thymic atrophy
and oxidative stress are believed to be important contributors to the pathogenesis during …
and oxidative stress are believed to be important contributors to the pathogenesis during …
Benefits of ascorbic acid in association with low-dose benznidazole in treatment of Chagas disease
MV Providello, ZA Carneiro, GB Portapilla… - Antimicrobial agents …, 2018 - Am Soc Microbiol
The acute phase of Chagas disease (CD) is characterized by high parasitic proliferation and
intense inflammation, exacerbating the generation of reactive oxygen species (ROS) and …
intense inflammation, exacerbating the generation of reactive oxygen species (ROS) and …
NADPH oxidase plays a role on ethanol-induced hypertension and reactive oxygen species generation in the vasculature
KC Marchi, CS Ceron, JJ Muniz… - Alcohol and …, 2016 - academic.oup.com
Aims Investigate the role of NADPH oxidase on ethanol-induced hypertension and vascular
oxidative stress. Methods Male Wistar rats were treated with ethanol (20% v/v). Results …
oxidative stress. Methods Male Wistar rats were treated with ethanol (20% v/v). Results …
Chronic ethanol consumption compromises neutrophil function in acute pulmonary Aspergillus fumigatus infection
NLSO Malacco, JAM Souza, FRB Martins, MA Rachid… - Elife, 2020 - elifesciences.org
Chronic ethanol consumption is a leading cause of mortality worldwide, with higher risks to
develop pulmonary infections, including Aspergillus infections. Mechanisms underlying …
develop pulmonary infections, including Aspergillus infections. Mechanisms underlying …
[HTML][HTML] Vascular injury associated with ethanol intake is driven by AT1 receptor and mitochondrial dysfunction
Abstract Background Renin-angiotensin (Ang II)-aldosterone system (RAAS) is crucial for
the cardiovascular risk associated with excessive ethanol consumption. Disturbs in …
the cardiovascular risk associated with excessive ethanol consumption. Disturbs in …
Pyrrolidine dithiocarbamate down‐regulates vascular matrix metalloproteinases and ameliorates vascular dysfunction and remodelling in renovascular hypertension
BACKGROUND AND PURPOSE Mounting evidence implicates matrix metalloproteinase
(MMP) in the vascular dysfunction and remodelling associated with hypertension. We tested …
(MMP) in the vascular dysfunction and remodelling associated with hypertension. We tested …
Melatonin regulates antioxidant defense and inflammatory response by activating Nrf2–dependent mechanisms and inhibiting NFkappaB expression in middle-aged T …
Oxidative stress with higher levels of leptin and inflammatory response are key processes
related to pathogenesis of both T. cruzi infection and aging. Nuclear factor erythroid 2 …
related to pathogenesis of both T. cruzi infection and aging. Nuclear factor erythroid 2 …
[HTML][HTML] Kaurene diterpene induces apoptosis in U87 human malignant glioblastoma cells by suppression of anti-apoptotic signals and activation of cysteine …
FS Lizarte Neto, DPC Tirapelli, SR Ambrosio… - Brazilian Journal of …, 2013 - SciELO Brasil
Gliomas are the most common and malignant primary brain tumors in humans. Studies have
shown that classes of kaurene diterpene have anti-tumor activity related to their ability to …
shown that classes of kaurene diterpene have anti-tumor activity related to their ability to …
[HTML][HTML] Bipolar affective disorder: pharmacotherapeutic profile and adherence to medication
AI Miasso, BP Carmo, CR Tirapelli - Revista da Escola de …, 2012 - SciELO Brasil
This cross-sectional and descriptive study aimed to verify the adherence of patients with
Bipolar Affective Disorder (BAD) to medication and to identify possible causes of adherence …
Bipolar Affective Disorder (BAD) to medication and to identify possible causes of adherence …