Left ventricular hypertrophy (LVH) is the major risk factor associated with myocardial failure.
An explanation for why a presumptive adaptation such as LVH would prove pathological has …

Growth or altered metabolism of nonmyocyte cells (cardiac fibroblasts, vascular smooth
muscle and endothelial cells) alters myocardial and vascular structure (remodeling) and …

Objective: Myocardial fibrosis is an important determinant of pathological hypertrophy. In two
experimental models of arterial hypertension the purpose of the study was (a) to determine …

Myocardial fibrosis is associated with an activated renin-angiotensin-aldosterone system
(RAAS). In renovascular hypertension, this presents as a reactive perivascular and …

Pathological left ventricular hypertrophy in renovascular hypertension is associated with the
accumulation of fibrillar collagen within the extracellular space and around intramyocardial …

Background—In arterial hypertension, left ventricular hypertrophy (LVH) includes myocyte
hypertrophy and fibrosis, which leads to LV diastolic dysfunction and, finally, heart failure. In …

Unlike the non-renin-dependent hypertension associated with infrarenal aorta banding, an
abnormal accumulation of fibrillar collagen occurs within the adventitia of intramural …

In arterial hypertension associated with primary or secondary hyperaldosteronism
myocardial fibrosis is an important determinant of pathologic hypertrophy. To further …

Activation of the renin-angiotensin-aldosterone system in arterial hypertension can lead to
remodeling of the myocardial collagen network, with progressive collagen accumulation in …

Left ventricular hypertrophy (LVH) in spontaneously hypertensive rats (SHR) is
accompanied by a structural remodeling of the myocardium that includes myocyte …