Therapeutic approach for patients with catecholaminergic polymorphic ventricular tachycardia: state of the art and future developments
C van der Werf, AH Zwinderman, AAM Wilde - Europace, 2012 - academic.oup.com
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited arrhythmia
syndrome characterized by bidirectional or polymorphic ventricular arrhythmias under …
syndrome characterized by bidirectional or polymorphic ventricular arrhythmias under …
Catecholaminergic polymorphic ventricular tachycardia
KV Lieve, C van der Werf, AA Wilde - Circulation Journal, 2016 - jstage.jst.go.jp
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited cardiac
arrhythmia disorder that is characterized by emotion-and exercise-induced polymorphic …
arrhythmia disorder that is characterized by emotion-and exercise-induced polymorphic …
The Lancet Commission to reduce the global burden of sudden cardiac death: a call for multidisciplinary action
E Marijon, K Narayanan, K Smith, S Barra, C Basso… - The Lancet, 2023 - thelancet.com
Despite major advancements in cardiovascular medicine, sudden cardiac death (SCD)
continues to be an enormous medical and societal challenge, claiming millions of lives …
continues to be an enormous medical and societal challenge, claiming millions of lives …
Flecainide therapy reduces exercise-induced ventricular arrhythmias in patients with catecholaminergic polymorphic ventricular tachycardia
C van der Werf, PJ Kannankeril, F Sacher… - Journal of the American …, 2011 - jacc.org
Objectives: This study evaluated the efficacy and safety of flecainide in addition to
conventional drug therapy in patients with catecholaminergic polymorphic ventricular …
conventional drug therapy in patients with catecholaminergic polymorphic ventricular …
Utility of post-mortem genetic testing in cases of sudden arrhythmic death syndrome
N Lahrouchi, H Raju, EM Lodder… - Journal of the American …, 2017 - jacc.org
Background: Sudden arrhythmic death syndrome (SADS) describes a sudden death with
negative autopsy and toxicological analysis. Cardiac genetic disease is a likely etiology …
negative autopsy and toxicological analysis. Cardiac genetic disease is a likely etiology …
Arrhythmogenic right ventricular dysplasia/cardiomyopathy: pathogenic desmosome mutations in index-patients predict outcome of family screening: Dutch …
MGPJ Cox, PA van der Zwaag, C van der Werf… - Circulation, 2011 - Am Heart Assoc
Background—Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) is an
autosomal dominant inherited disease with incomplete penetrance and variable expression …
autosomal dominant inherited disease with incomplete penetrance and variable expression …
Derivation and validation of a simple exercise-based algorithm for prediction of genetic testing in relatives of LQTS probands
RW Sy, C van der Werf, IS Chattha, P Chockalingam… - Circulation, 2011 - Am Heart Assoc
Background—Genetic testing can diagnose long-QT syndrome (LQTS) in asymptomatic
relatives of patients with an identified mutation; however, it is costly and subject to …
relatives of patients with an identified mutation; however, it is costly and subject to …
Diagnostic yield in sudden unexplained death and aborted cardiac arrest in the young: the experience of a tertiary referral center in The Netherlands
C van der Werf, N Hofman, HL Tan, PF van Dessel… - Heart Rhythm, 2010 - Elsevier
BACKGROUND: In sudden unexplained death (SUD) in the young (age 1–50 years),
cardiologic and genetic examination in surviving relatives may unmask the cause of death in …
cardiologic and genetic examination in surviving relatives may unmask the cause of death in …
Incidence, causes, and outcomes of out-of-hospital cardiac arrest in children: a comprehensive, prospective, population-based study in the Netherlands
A Bardai, J Berdowski, C Van Der Werf, MT Blom… - Journal of the American …, 2011 - jacc.org
Objectives: This study sought to determine comprehensively the incidence of pediatric out-of-
hospital cardiac arrest (OHCA) and its contribution to total pediatric mortality, the causes of …
hospital cardiac arrest (OHCA) and its contribution to total pediatric mortality, the causes of …
Familial evaluation in catecholaminergic polymorphic ventricular tachycardia: Disease penetrance and expression in cardiac ryanodine receptor mutation–carrying …
C van der Werf, I Nederend, N Hofman… - Circulation …, 2012 - Am Heart Assoc
Background—Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited
arrhythmia syndrome associated with mutations in the cardiac ryanodine receptor gene …
arrhythmia syndrome associated with mutations in the cardiac ryanodine receptor gene …