[HTML][HTML] IGF-1 and IGFBP-3 in Inflammatory Cachexia

…, Á Moreno-Ruperez, D González-Hedström… - International Journal of …, 2021 - mdpi.com
Inflammation induces a wide response of the neuroendocrine system, which leads to
modifications in all the endocrine axes. The hypothalamic–growth hormone (GH)–insulin …

[PDF][PDF] Obesity-associated hyperleptinemia alters the gliovascular interface of the hypothalamus to promote hypertension

…, AL García-Villalón, D González-Hedström… - Cell metabolism, 2021 - cell.com
Pathologies of the micro-and macrovascular systems are a hallmark of the metabolic
syndrome, which can lead to chronically elevated blood pressure. However, the underlying …

Role of hormones in sarcopenia

T Priego, AI Martín, D González-Hedström… - Vitamins and …, 2021 - Elsevier
Aging involves numerous changes in body composition that include a decrease in skeletal
muscle mass. The gradual reduction in muscle mass is associated with a simultaneous …

[HTML][HTML] Beneficial effects of an aged black garlic extract in the metabolic and vascular alterations induced by a high fat/sucrose diet in male rats

S Amor, D González-Hedström, B Martín-Carro… - Nutrients, 2019 - mdpi.com
Aged black garlic (ABG) is a functional food with antioxidant and anti-inflammatory
properties. Recent studies also report its beneficial metabolic effects in a context of obesity …

[HTML][HTML] Antihypertensive Effects of an Optimized Aged Garlic Extract in Subjects with Grade I Hypertension and Antihypertensive Drug Therapy: A Randomized, Triple …

…, MI Morán-Valero, D González-Hedström… - Nutrients, 2023 - mdpi.com
The use of garlic (Allium sativum) for treating arterial hypertension has been recognized as
effective for several decades. However, tolerance to treatment is low, and several …

[HTML][HTML] Protective effects of extra virgin olive oil against storage-induced omega 3 fatty acid oxidation of algae oil

D González-Hedström, M Granado, AM Inarejos-García - NFS Journal, 2020 - Elsevier
The low oxidative stability of polyunsaturated fatty acids (PUFA) in omega-3 supplements
may cause the formation of compounds that may have negative healthy effects. Extra virgin …

[HTML][HTML] Olive leaf extract supplementation to old wistar rats attenuates aging-induced sarcopenia and increases insulin sensitivity in adipose tissue and skeletal …

D González-Hedström, T Priego, S Amor… - Antioxidants, 2021 - mdpi.com
Aging is associated with increased visceral adiposity and a decrease in the amount of brown
adipose tissue and muscle mass, known as sarcopenia, which results in the development of …

[HTML][HTML] Supplementation with a Carob (Ceratonia siliqua L.) Fruit Extract Attenuates the Cardiometabolic Alterations Associated with Metabolic Syndrome in Mice

M de la Fuente-Fernández, D González-Hedström… - Antioxidants, 2020 - mdpi.com
The incidence of metabolic syndrome (MetS) is increasing worldwide which makes
necessary the finding of new strategies to treat and/or prevent it. The aim of this study was to …

[HTML][HTML] Olive leaf extract supplementation improves the vascular and metabolic alterations associated with aging in Wistar rats

D González-Hedström, ÁL García-Villalón, S Amor… - Scientific Reports, 2021 - nature.com
Olive leaves are rich in bioactive substances which exert anti-inflammatory, antioxidant,
insulin-sensitizing and antihypertensive effects. The aim of this study was to analyze the …

[HTML][HTML] Addition of olive leaf extract to a mixture of algae and extra virgin olive oils decreases fatty acid oxidation and synergically attenuates age-induced …

D González-Hedström, M de La Fuente-Fernandez… - Antioxidants, 2021 - mdpi.com
Olive-derived products, such as virgin olive oil (EVOO) and/or olive leaf extracts (OLE), exert
anti-inflammatory, insulin-sensitizing and antihypertensive properties and may be useful for …