User profiles for "author:Daniel C Andersson"
Daniel C AnderssonKarolinska Institutet Verified email at ki.se Cited by 3276 |
Reactive oxygen/nitrogen species and contractile function in skeletal muscle during fatigue and recovery
AJ Cheng, T Yamada, DE Rassier… - The Journal of …, 2016 - Wiley Online Library
The production of reactive oxygen/nitrogen species (ROS/RNS) is generally considered to
increase during physical exercise. Nevertheless, direct measurements of ROS/RNS often …
increase during physical exercise. Nevertheless, direct measurements of ROS/RNS often …
Fixing ryanodine receptor Ca2+ leak–a novel therapeutic strategy for contractile failure in heart and skeletal muscle
DC Andersson, AR Marks - Drug discovery today: disease mechanisms, 2010 - Elsevier
A crucial component in regulating cardiac and skeletal muscles contractility is the release of
Ca2+ via ryanodine receptor (RyR) Ca2+ release channels in the sarcoplasmic reticulum …
Ca2+ via ryanodine receptor (RyR) Ca2+ release channels in the sarcoplasmic reticulum …
[PDF][PDF] Ryanodine receptor oxidation causes intracellular calcium leak and muscle weakness in aging
DC Andersson, MJ Betzenhauser, S Reiken, AC Meli… - Cell metabolism, 2011 - cell.com
Age-related loss of muscle mass and force (sarcopenia) contributes to disability and
increased mortality. Ryanodine receptor 1 (RyR1) is the skeletal muscle sarcoplasmic …
increased mortality. Ryanodine receptor 1 (RyR1) is the skeletal muscle sarcoplasmic …
Excess TGF-β mediates muscle weakness associated with bone metastases in mice
Cancer-associated muscle weakness is a poorly understood phenomenon, and there is no
effective treatment. Here we find that seven different mouse models of human osteolytic …
effective treatment. Here we find that seven different mouse models of human osteolytic …
Mitochondrial production of reactive oxygen species contributes to the β‐adrenergic stimulation of mouse cardiomycytes
DC Andersson, J Fauconnier, T Yamada… - The Journal of …, 2011 - Wiley Online Library
Non‐technical summary When under stress, the heart beat becomes stronger, in part due to
enhanced fluxes of Ca2+ at the level of the cardiac cell. It is known that this effect is …
enhanced fluxes of Ca2+ at the level of the cardiac cell. It is known that this effect is …
[HTML][HTML] Endurance exercise increases skeletal muscle kynurenine aminotransferases and plasma kynurenic acid in humans
M Schlittler, M Goiny, LZ Agudelo… - … of Physiology-Cell …, 2016 - journals.physiology.org
Physical exercise has emerged as an alternative treatment for patients with depressive
disorder. Recent animal studies show that exercise protects from depression by increased …
disorder. Recent animal studies show that exercise protects from depression by increased …
Genetically enhancing mitochondrial antioxidant activity improves muscle function in aging
A Umanskaya, G Santulli, W Xie… - Proceedings of the …, 2014 - National Acad Sciences
Age-related skeletal muscle dysfunction is a leading cause of morbidity that affects up to half
the population aged 80 or greater. Here we tested the effects of increased mitochondrial …
the population aged 80 or greater. Here we tested the effects of increased mitochondrial …
Erythrocytes from patients with type 2 diabetes induce endothelial dysfunction via arginase I
Background: Cardiovascular complications are major clinical problems in type 2 diabetes
mellitus (T2DM). The authors previously demonstrated a crucial role of red blood cells …
mellitus (T2DM). The authors previously demonstrated a crucial role of red blood cells …
Association between rheumatoid arthritis and risk of ischemic and nonischemic heart failure
Background: It is unknown whether the increased risk of heart failure (HF) in rheumatoid
arthritis (RA) is independent of ischemic heart disease (IHD). Objectives: This study sought …
arthritis (RA) is independent of ischemic heart disease (IHD). Objectives: This study sought …
[HTML][HTML] Assessment of muscle mass and strength in mice
Muscle weakness is an important phenotype of many diseases that is linked to impaired
locomotion and increased mortality. The force that a muscle can generate is determined …
locomotion and increased mortality. The force that a muscle can generate is determined …