Abstract Objective This EAS Consensus Panel critically appraised evidence relevant to the
benefit to risk relationship of functional foods with added plant sterols and/or plant stanols …

The cholesterol-lowering effect of phytosterols has been extensively studied, and
consumption of phytosterols is among the recommendations to lower LDL-cholesterol …

The recent discovery of transporters in the intestinal mucosa and the canalicular membrane
has given new insights into the regulation of intestinal absorption as well as the biliary …

Background—Ezetimibe has been shown to inhibit cholesterol absorption in animal models,
but studies on cholesterol absorption in humans have not been performed thus far. Methods …

We have investigated whether side chain-hydroxylated cholesterol species are important for
elimination of cholesterol from the brain. Plasma concentrations of 24-hydroxycholesterol …

We have previously demonstrated that the brain contains about 80% of the 24S-
hydroxycholesterol in the human body and that there is a net flux of this steroid from the …

Nonalcoholic steatohepatitis (NASH) involves liver lipid accumulation (steatosis) combined
with hepatic inflammation. The transition towards hepatic inflammation represents a key step …

In a randomized, placebo‐controlled, double‐blind study, we investigated whether statins
alter cholesterol metabolites and reduce Aβ levels in the cerebrospinal fluid of 44 patients …

Alzheimer's disease (AD) is characterized by the presence of senile plaques, neurofibrillary
tangles, and neuronal cell loss associated with membrane cholesterol release. 24S …

High-density lipoprotein (HDL) mediates reverse cholesterol transport and is known to be
protective against atherosclerosis. In addition, HDL has potent anti-inflammatory properties …