Background Mitral-valve repair can be accomplished with an investigational procedure that
involves the percutaneous implantation of a clip that grasps and approximates the edges of …

The adult heart lacks reserve cardiocytes and cannot regenerate. Therefore, a large acute
myocardial infarction often develops into congestive heart failure. To attempt to prevent this …

The Frank-Starling relationship generally has been examined with filling pressure as the
index of preload, resulting in a curvilinear function that plateaus at higher filling pressures …

Objectives: We undertook a prospective multicenter single-arm study to evaluate the
feasibility, safety, and efficacy of the MitraClip system (Evalve Inc., Menlo Park, California) …

Abstract Background: In EVEREST II (Endovascular Valve Edge-to-Edge Repair Study),
treatment of mitral regurgitation (MR) with a novel percutaneous device showed superior …

BACKGROUND Survival after coronary artery bypass graft surgery (CABG) and medical
therapy in patients with coronary artery disease (CAD) has been studied in both randomized …

Objectives: The EVEREST II (Endovascular Valve Edge-to-Edge Repair) High Risk Study
(HRS) assessed the safety and effectiveness of the MitraClip device (Abbott Vascular, Santa …

Objectives: This study sought to evaluate 4-year outcomes of percutaneous repair versus
surgery for mitral regurgitation. Background: Transcatheter therapies are being developed to …

Abstract Background: The EVEREST II (Endovascular Valve Edge-to-Edge REpair STudy)
High-Risk registry and REALISM Continued Access Study High-Risk Arm are prospective …

OBJECTIVE: In some respects, outcome reporting in valvular surgery has been hampered
by focusing on specific populations, reluctance to publish high-risk subgroups, and possibly …