[HTML][HTML] Clinical recommendations for cardiovascular magnetic resonance mapping of T1, T2, T2* and extracellular volume: a consensus statement by the Society for …

DR Messroghli, JC Moon, VM Ferreira… - Journal of …, 2016 - Elsevier
Parametric mapping techniques provide a non-invasive tool for quantifying tissue alterations
in myocardial disease in those eligible for cardiovascular magnetic resonance (CMR) …

[HTML][HTML] Myocardial T1 mapping and extracellular volume quantification: a Society for Cardiovascular Magnetic Resonance (SCMR) and CMR Working Group of the …

JC Moon, DR Messroghli, P Kellman… - Journal of …, 2013 - Elsevier
Rapid innovations in cardiovascular magnetic resonance (CMR) now permit the routine
acquisition of quantitative measures of myocardial and blood T1 which are key tissue …

Developing therapies for heart failure with preserved ejection fraction: current state and future directions

J Butler, GC Fonarow, MR Zile, CS Lam, L Roessig… - JACC: Heart Failure, 2014 - jacc.org
The burden of heart failure with preserved ejection fraction (HFpEF) is considerable and is
projected to worsen. To date, there are no approved therapies available for reducing …

Prognostic value of late gadolinium enhancement cardiovascular magnetic resonance in cardiac amyloidosis

M Fontana, S Pica, P Reant, A Abdel-Gadir, TA Treibel… - Circulation, 2015 - Am Heart Assoc
Background—The prognosis and treatment of the 2 main types of cardiac amyloidosis,
immunoglobulin light chain (AL) and transthyretin (ATTR) amyloidosis, are substantially …

Association between extracellular matrix expansion quantified by cardiovascular magnetic resonance and short-term mortality

TC Wong, K Piehler, CG Meier, SM Testa, AM Klock… - Circulation, 2012 - Am Heart Assoc
Background—Extracellular matrix expansion may be a fundamental feature of adverse
myocardial remodeling, it appears to be treatable, and its measurement may improve risk …

Myocardial interstitial fibrosis in heart failure: biological and translational perspectives

A González, EB Schelbert, J Díez, J Butler - Journal of the American …, 2018 - jacc.org
Myocardial interstitial fibrosis contributes to left ventricular dysfunction leading to the
development of heart failure. Basic research has provided abundant evidence for the …

Myocardial extracellular volume fraction quantified by cardiovascular magnetic resonance is increased in diabetes and associated with mortality and incident heart …

TC Wong, KM Piehler, IA Kang, A Kadakkal… - European heart …, 2014 - academic.oup.com
Aims Diabetes may promote myocardial extracellular matrix (ECM) expansion that increases
vulnerability. We hypothesized that:(i) type 2 diabetes would be associated with quantitative …

Prevalence and prognosis of unrecognized myocardial infarction determined by cardiac magnetic resonance in older adults

EB Schelbert, JJ Cao, S Sigurdsson, T Aspelund… - Jama, 2012 - jamanetwork.com
Context Unrecognized myocardial infarction (MI) is prognostically important.
Electrocardiography (ECG) has limited sensitivity for detecting unrecognized MI (UMI) …

[HTML][HTML] Myocardial extravascular extracellular volume fraction measurement by gadolinium cardiovascular magnetic resonance in humans: slow infusion versus …

EB Schelbert, SM Testa, CG Meier, WJ Ceyrolles… - Journal of …, 2011 - Elsevier
Background Myocardial extravascular extracellular volume fraction (Ve) measures quantify
diffuse fibrosis not readily detectable by conventional late gadolinium (Gd) enhancement …

Pirfenidone in heart failure with preserved ejection fraction: a randomized phase 2 trial

GA Lewis, S Dodd, D Clayton, E Bedson, H Eccleson… - Nature Medicine, 2021 - nature.com
In heart failure with preserved ejection fraction (HFpEF), the occurrence of myocardial
fibrosis is associated with adverse outcome. Whether pirfenidone, an oral antifibrotic agent …