User profiles for "author:G. Fragasso"
 | Gabriele FragassoOspedale San Raffaele, Milano, Italy Verified email at hsr.it Cited by 7127 |
Rationale and benefits of trimetazidine by acting on cardiac metabolism in heart failure
YM Lopatin, GMC Rosano, G Fragasso… - International journal of …, 2016 - Elsevier
Heart failure is a systemic and multiorgan syndrome with metabolic failure as a fundamental
mechanism. As a consequence of its impaired metabolism, other processes are activated in …
mechanism. As a consequence of its impaired metabolism, other processes are activated in …
Short-and long-term beneficial effects of trimetazidine in patients with diabetes and ischemic cardiomyopathy
G Fragasso, PM Piatti, L Monti, A Palloshi, E Setola… - American heart …, 2003 - Elsevier
BACKGROUND: Trimetazidine (TMZ) has been shown to partially inhibit free fatty acid
oxidation by shifting substrate utilization from fatty acid to glucose. The aim of this study was …
oxidation by shifting substrate utilization from fatty acid to glucose. The aim of this study was …
Effects of metabolic modulation by trimetazidine on left ventricular function and phosphocreatine/adenosine triphosphate ratio in patients with heart failure
Aims The addition of trimetazidine to standard treatment has been shown to improve left
ventricular (LV) function in patients with heart failure. The aim of this study is to non …
ventricular (LV) function in patients with heart failure. The aim of this study is to non …
A randomized clinical trial of trimetazidine, a partial free fatty acid oxidation inhibitor, in patients with heart failure
G Fragasso, A Palloshi, P Puccetti, C Silipigni… - Journal of the American …, 2006 - jacc.org
Objectives: This study sought to assess whether the long-term addition of trimetazidine to
conventional treatment could improve functional class, exercise tolerance, and left …
conventional treatment could improve functional class, exercise tolerance, and left …
[HTML][HTML] Anthracycline-induced cardiotoxicity: A multicenter randomised trial comparing two strategies for guiding prevention with enalapril: The International …
…, P Vallerio, L Marbello, E Sala, G Fragasso… - European journal of …, 2018 - Elsevier
Background Troponin changes over time have been suggested to allow for an early
diagnosis of cardiac injury ensuing cancer chemotherapy; cancer patients with troponin …
diagnosis of cardiac injury ensuing cancer chemotherapy; cancer patients with troponin …
Sodium–glucose co‐transporter 2 inhibitors in heart failure: beyond glycaemic control. A position paper of the Heart Failure Association of the European Society of …
Heart failure (HF) is common and associated with a poor prognosis, despite advances in
treatment. Over the last decade cardiovascular outcome trials with sodium–glucose co …
treatment. Over the last decade cardiovascular outcome trials with sodium–glucose co …
Association of insulin resistance, hyperleptinemia, and impaired nitric oxide release with in-stent restenosis in patients undergoing coronary stenting
PM Piatti, C Di Mario, LD Monti, G Fragasso, F Sgura… - Circulation, 2003 - Am Heart Assoc
Background—Previously undiagnosed diabetes, impaired glucose tolerance, and insulin
resistance are common in patients with acute myocardial infarction and coronary heart …
resistance are common in patients with acute myocardial infarction and coronary heart …
Effect of oral L-arginine on blood pressure and symptoms and endothelial function in patients with systemic hypertension, positive exercise tests, and normal coronary …
A Palloshi, G Fragasso, PM Piatti, LD Monti… - The American journal of …, 2004 - Elsevier
Thirteen hypertensive patients with microvascular angina were studied before and after
receiving oral l-arginine (4 weeks, 2 g, 3 times daily). l-arginine significantly improved …
receiving oral l-arginine (4 weeks, 2 g, 3 times daily). l-arginine significantly improved …
Effect of partial fatty acid oxidation inhibition with trimetazidine on mortality and morbidity in heart failure: results from an international multicentre retrospective cohort …
OBJECTIVES: The aim of this cohort study was to retrospectively evaluate, in patients with
chronic heart failure (CHF), the long term effect of trimetazidine (TMZ) on morbidity and …
chronic heart failure (CHF), the long term effect of trimetazidine (TMZ) on morbidity and …
Effects of trimetazidine on ischemic left ventricular dysfunction in patients with coronary artery disease
C Lu, P Dabrowski, G Fragasso… - American Journal of …, 1998 - ajconline.org
Trimetazidine 1 (2, 3, 4, trimethoxybenzyl-piperazine dihydrochloride)(TMZ) has been
reported to exert anti-ischemic properties without affecting myocardial oxygen consumption …
reported to exert anti-ischemic properties without affecting myocardial oxygen consumption …