User profiles for "author:Gianluca Lucchese"

Gianluca Lucchese

Guy's and St. Thomas' NHS Foundation Trust
Verified email at gstt.nhs.uk
Cited by 649

Prevention of cardiac surgery–associated acute kidney injury by implementing the KDIGO guidelines in high-risk patients identified by biomarkers: The PrevAKI …

A Zarbock, M Küllmar, M Ostermann… - Anesthesia & …, 2021 - journals.lww.com
BACKGROUND: Prospective, single-center trials have shown that the implementation of the
Kidney Disease: Improving Global Outcomes (KDIGO) recommendations in high-risk …

Management of Patients With Severe Mitral Annular Calcification: JACC State-of-the-Art Review

O Chehab, R Roberts-Thomson, A Bivona, H Gill… - Journal of the American …, 2022 - jacc.org
Mitral annular calcification (MAC) is a common and challenging pathologic condition,
especially in the context of an aging society. Surgical mitral valve intervention in patients …

Two decades of experience with the Ross operation in neonates, infants and children from the Italian Paediatric Ross Registry

GB Luciani, G Lucchese, A Carotti, G Brancaccio… - Heart, 2014 - heart.bmj.com
Objective Children undergoing Ross operation were expected to have longer autograft, but
shorter homograft durability compared with adults. In order to define the outcome in the …

[HTML][HTML] Hyperglycemia and angiotensin II cooperate to enhance collagen I deposition by cardiac fibroblasts through a ROS-STAT3-dependent mechanism

T Fiaschi, F Magherini, T Gamberi, G Lucchese… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Cardiac fibroblasts significantly contribute to diabetes-induced structural and functional
changes in the myocardium. The objective of the present study was to determine the effects …

Hyperglycemia Activates JAK2 Signaling Pathway in Human Failing Myocytes via Angiotensin II–Mediated Oxidative Stress

A Modesti, I Bertolozzi, T Gamberi, M Marchetta… - Diabetes, 2005 - Am Diabetes Assoc
Hyperglycemia was reported to enhance angiotensin (Ang) II generation in rat
cardiomyocytes, and Ang II inhibition reduces cardiovascular morbidity and mortality in …

Reparative surgery of the pulmonary autograft: experience with Ross reoperations

GB Luciani, G Lucchese, F De Rita… - European journal of …, 2012 - academic.oup.com
OBJECTIVE Autograft valve and root pathology is the leading cause of Ross procedure
failure. To define risk and outcome of autograft valve/root repair at reoperation, a 17-year …

Conventional aortic root vs valve-sparing root replacement surgery in aortic dilatation syndromes: a comparison of mortality and postoperative complications

HN Rashid, O Chehab, H Hurrell… - Expert Review of …, 2023 - Taylor & Francis
Introduction Conventional aortic root and valve-sparing root replacement surgery are two
current surgical treatments for aortic dilatation syndromes. This review article aims to review …

[HTML][HTML] Minimal-access median sternotomy for aortic valve replacement

GB Luciani, G Lucchese - Journal of Thoracic Disease, 2013 - ncbi.nlm.nih.gov
A variety of minimally-invasive approaches for aortic valve replacement (AVR) have been
developed and are increasingly being utilized. The different approaches described, such as …

Diagnosis of infection in paediatric veno-arterial cardiac extracorporeal membrane oxygenation: role of procalcitonin and C-reactive protein

A Rungatscher, A Merlini, F De Rita… - European Journal of …, 2013 - academic.oup.com
OBJECTIVES Plasma concentration of procalcitonin (PCT) and its value in the diagnosis of
infection in paediatric patients treated with extracorporeal membrane oxygenation (ECMO) …

Selective cerebro‐myocardial perfusion in complex congenital aortic arch pathology: a novel technique

F De Rita, G Lucchese, L Barozzi, T Menon… - Artificial …, 2011 - Wiley Online Library
Simultaneous cerebro‐myocardial perfusion has been described in neonatal and infant arch
surgery, suggesting a reduction in cardiac morbidity. Here reported is a novel technique for …