Myocardial tissue characterization and fibrosis by imaging

TD Karamitsos, A Arvanitaki, H Karvounis… - Cardiovascular …, 2020 - jacc.org
Myocardial fibrosis, either focal or diffuse, is a common feature of many cardiac diseases
and is associated with a poor prognosis for major adverse cardiovascular events. Although …

Adult congenital heart disease: a paradigm of epidemiological change

…, T Panagiotidis, MA Gatzoulis, H Karvounis - International journal of …, 2016 - Elsevier
Increasing survival rates for patients with congenital heart disease (CHD) represent a major
achievement of modern medicine. Despite incredible progress been made in diagnosis …

The role of uric acid in stroke: the issue remains unresolved

HV Dimitroula, AI Hatzitolios, HI Karvounis - The neurologist, 2008 - journals.lww.com
Background: Although in the past decade a large number of studies have been performed to
identify the relationship between uric acid and stroke, the issue remains unresolved and it is …

Switching to riociguat versus maintenance therapy with phosphodiesterase-5 inhibitors in patients with pulmonary arterial hypertension (REPLACE): a multicentre …

…, H Wilkens, H Wirtz, H Karvounis… - The Lancet …, 2021 - thelancet.com
Background Riociguat and phosphodiesterase-5 inhibitors (PDE5i), approved for the
treatment of pulmonary arterial hypertension (PAH), act on the same pathway via different …

Early diastolic impairment of diabetic heart: the significance of right ventricle

TD Karamitsos, HI Karvounis, EG Dalamanga… - International journal of …, 2007 - Elsevier
BACKGROUND: Left ventricular diastolic dysfunction represents the earliest preclinical
manifestation of diabetic cardiomyopathy. Right ventricular function has not been studied in …

Efficacy and safety of high dose versus low dose furosemide with or without dopamine infusion: the Dopamine in Acute Decompensated Heart Failure II (DAD-HF II) …

…, L Mantziari, G Giannakoulas, H Karvounis… - International journal of …, 2014 - Elsevier
Aims The role of low-dose dopamine infusion in patients with acute decompensated heart
failure (ADHF) remains controversial. We aim to evaluate the efficacy and safety of high …

Clinical characteristics and natural history of hypertrophic cardiomyopathy with midventricular obstruction

…, S Hadjimiltiades, C Pliakos, H Karvounis… - Circulation …, 2013 - jstage.jst.go.jp
Background: The prevalence, clinical characteristics and natural history of patients with
hypertrophic cardiomyopathy (HCM) and midventricular obstruction (MVO) have not been …

“Missing” acute coronary syndrome hospitalizations during the COVID‐19 era in Greece: Medical care avoidance combined with a true reduction in incidence?

…, N Iakovis, P Grammata, H Karvounis… - Clinical …, 2020 - Wiley Online Library
Background Reports from countries severely hit by the COVID‐19 pandemic suggest a
decline in acute coronary syndrome (ACS)‐related hospitalizations. The generalizability of …

Accurate and reproducible reconstruction of coronary arteries and endothelial shear stress calculation using 3D OCT: comparative study to 3D IVUS and 3D QCA

…, S Nakamura, JHC Reiber, F Rybicki, H Karvounis… - Atherosclerosis, 2015 - Elsevier
Abstract Background Geometrically-correct 3D OCT is a new imaging modality with the
potential to investigate the association of local hemodynamic microenvironment with OCT …

Left ventricular outflow tract obstruction as a risk factor for sudden cardiac death in hypertrophic cardiomyopathy

…, G Savvopoulos, A Ziakas, H Karvounis… - The American journal of …, 2009 - Elsevier
The effect of left ventricular outflow tract obstruction (LVOTO) at rest on the incidence of
sudden death (SD) in patients with hypertrophic cardiomyopathy is rather conflicting. The …