PEComas, occasionally associated with the tuberous sclerosis complex, are defined by the
presence of perivascular epithelioid cells that coexpress muscle and melanocytic markers …

The explosion in modern methods and techniques for cell and molecular biology within the
last few years has provided a plethora of clues for the understanding of complex biological …

Sepsis is a frequent complication of multiple organ dysfunction syndrome and remains a
major problem of intensive care medicine. It is also a common factor in the final cause of …

Metastatic growth in distant organs is the major cause of cancer mortality. The development
of metastasis is a multistage process with several rate-limiting steps. Although dissemination …

Alterations of TGF-β signaling have been described in colorectal cancer, although the
molecular consequences are largely unknown. By using transgenic mice overexpressing …

Human asthma is associated with airway infiltration by T helper 2 (TH2) lymphocytes. We
observed reduced expression of the TH1 transcription factor, T-bet, in T cells from airways of …

Estrogen receptor (ER) expression and proliferative activity are established prognostic
factors in breast cancer. In a search for additional prognostic motifs, we analyzed the gene …

The pro-inflammatory cytokine interleukin (IL)-6 (refs. 1–5) can bind to cells lacking the IL-6
receptor (IL-6R) when it forms a complex with the soluble IL-6R (sIL-6R)(trans signaling) 5 …

Purpose: Despite a rapid spread of the technique, very little is known about the laser-tissue
interaction in endovenous laser treatment (EVLT). We evaluated EVLT of the incompetent …

Background The proinflammatory cytokines interleukin 1β (IL-1β) and IL-18 are central
players in the pathogenesis of inflammatory bowel disease (IBD). In response to a variety of …