Prevention of cardiac dysfunction during adjuvant breast cancer therapy (PRADA): a 2× 2 factorial, randomized, placebo-controlled, double-blind clinical trial of …

G Gulati, SL Heck, AH Ree, P Hoffmann… - European heart …, 2016 - academic.oup.com
Aims Contemporary adjuvant treatment for early breast cancer is associated with improved
survival but at the cost of increased risk of cardiotoxicity and cardiac dysfunction. We tested …

Novel biomarkers of cardiovascular disease: applications in clinical practice

MN Lyngbakken, PL Myhre, H Røsjø… - Critical reviews in …, 2019 - Taylor & Francis
Measurement of biomarkers has revolutionized the work-up of patients with suspected
cardiovascular disease. The most widely used contemporary cardiovascular biomarkers are …

[HTML][HTML] Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials

C Axfors, AM Schmitt, P Janiaud, J Van't Hooft… - Nature …, 2021 - nature.com
Substantial COVID-19 research investment has been allocated to randomized clinical trials
(RCTs) on hydroxychloroquine/chloroquine, which currently face recruitment challenges or …

The gut microbial profile in patients with primary sclerosing cholangitis is distinct from patients with ulcerative colitis without biliary disease and healthy controls

M Kummen, K Holm, JA Anmarkrud, S Nygård… - Gut, 2017 - gut.bmj.com
Objective Gut microbiota could influence gut, as well as hepatic and biliary immune
responses. We therefore thoroughly characterised the gut microbiota in primary sclerosing …

Prognostic value of cardiac troponin I measured with a highly sensitive assay in patients with stable coronary artery disease

T Omland, MA Pfeffer, SD Solomon… - Journal of the American …, 2013 - jacc.org
Objectives: The aims of this study were to assess the prognostic value of cardiac troponin I
levels, measured with a new high-sensitivity assay, in low-risk patients with stable coronary …

[HTML][HTML] Circulating microRNAs and aerobic fitness–the HUNT-Study

A Bye, H Røsjø, ST Aspenes, G Condorelli, T Omland… - PloS one, 2013 - journals.plos.org
Aerobic fitness, measured as maximal oxygen uptake (VO2max), is a good indicator of
cardiovascular health, and a strong predictor of cardiovascular mortality. Biomarkers …

[HTML][HTML] Circulating high sensitivity troponin T in severe sepsis and septic shock: distribution, associated factors, and relation to outcome

H Røsjø, M Varpula, TA Hagve, S Karlsson… - Intensive care …, 2011 - Springer
Purpose To assess the clinical utility of a recently developed highly sensitive cardiac
troponin T (hs-cTnT) assay for providing prognostic information on patients with sepsis …

[HTML][HTML] Targeting NAD+ in translational research to relieve diseases and conditions of metabolic stress and ageing

BC Gilmour, R Gudmundsrud, J Frank, A Hov… - Mechanisms of Ageing …, 2020 - Elsevier
Nicotinamide adenine dinucleotide (NAD+) plays a fundamental role in life and health
through the regulation of energy biogenesis, redox homeostasis, cell metabolism, and the …

Enhanced liver fibrosis score predicts transplant‐free survival in primary sclerosing cholangitis

M Vesterhus, JR Hov, A Holm, E Schrumpf, S Nygård… - Hepatology, 2015 - journals.lww.com
There is a need to determine biomarkers reflecting disease activity and prognosis in primary
sclerosing cholangitis (PSC). We evaluated the prognostic utility of the enhanced liver …

Prevention of cardiac dysfunction during adjuvant breast cancer therapy (PRADA): extended follow-up of a 2× 2 factorial, randomized, placebo-controlled, double …

SL Heck, A Mecinaj, AH Ree, P Hoffmann… - Circulation, 2021 - Am Heart Assoc
Background: Adjuvant breast cancer therapy containing anthracyclines with or without anti–
human epidermal growth factor receptor–2 antibodies and radiotherapy is associated with …