User profiles for "author:Hisashi Sawada"
 | Hisashi SawadaSaha Cardiovascular Research Center, University of Kentucky Verified email at uky.edu Cited by 1589 |
Renin-angiotensin system and cardiovascular functions
CH Wu, S Mohammadmoradi, JZ Chen… - … , and vascular biology, 2018 - Am Heart Assoc
Wu et al The RAS and Cardiovascular Functions e109 homocysteine decreased
antihypertensive effect of enalapril, an ACE inhibitor, in chronic hypertensive patients. 61 …
antihypertensive effect of enalapril, an ACE inhibitor, in chronic hypertensive patients. 61 …
Surgical techniques and innovations in living related liver transplantation.
K Tanaka, S Uemoto, Y Tokunaga, S Fujita… - Annals of …, 1993 - ncbi.nlm.nih.gov
The authors successfully performed a series of 33 living related liver transplantations (LRLT)
on children (15 males and 18 females, ranging from 7 months to 15 years of age) from June …
on children (15 males and 18 females, ranging from 7 months to 15 years of age) from June …
Twenty years of studying AngII (angiotensin II)-induced abdominal aortic pathologies in mice: continuing questions and challenges to provide insight into the human …
AngII (angiotensin II) infusion in mice has been used to provide mechanistic insight into
human abdominal aortic aneurysms for over 2 decades. This is a technically facile animal …
human abdominal aortic aneurysms for over 2 decades. This is a technically facile animal …
Recent advances in understanding the molecular pathophysiology of angiotensin II receptors; Lessons from cell-selective receptor deletion in mice
The renin-angiotensin system (RAS) is an essential hormonal system involved in water and
sodium reabsorption, renal blood flow regulation, and arterial constriction. Systemic …
sodium reabsorption, renal blood flow regulation, and arterial constriction. Systemic …
Smooth muscle cells derived from second heart field and cardiac neural crest reside in spatially distinct domains in the media of the ascending aorta—brief report
H Sawada, DL Rateri, JJ Moorleghen… - … , and vascular biology, 2017 - Am Heart Assoc
Objective—Smooth muscle cells (SMCs) of the proximal thoracic aorta are embryonically
derived from the second heart field (SHF) and cardiac neural crest (CNC). However …
derived from the second heart field (SHF) and cardiac neural crest (CNC). However …
Accuracy of OCT, grayscale IVUS, and their combination for the diagnosis of coronary TCFA: an ex vivo validation study
K Fujii, H Hao, M Shibuya, T Imanaka… - JACC: Cardiovascular …, 2015 - jacc.org
Objectives: This study sought to assess the accuracy of optical coherence tomography
(OCT), gray-scale intravascular ultrasound (IVUS), and their combination for detecting thin …
(OCT), gray-scale intravascular ultrasound (IVUS), and their combination for detecting thin …
Aortic iron overload with oxidative stress and inflammation in human and murine abdominal aortic aneurysm
H Sawada, H Hao, Y Naito, M Oboshi… - … , and vascular biology, 2015 - Am Heart Assoc
Objective—Although iron is an essential element for maintaining physiological function,
excess iron leads to tissue damage caused by oxidative stress and inflammation. Oxidative …
excess iron leads to tissue damage caused by oxidative stress and inflammation. Oxidative …
Exome-wide evaluation of rare coding variants using electronic health records identifies new gene–phenotype associations
The clinical impact of rare loss-of-function variants has yet to be determined for most genes.
Integration of DNA sequencing data with electronic health records (EHRs) could enhance …
Integration of DNA sequencing data with electronic health records (EHRs) could enhance …
Atorvastatin ameliorates cardiac fibrosis and improves left ventricular diastolic function in hypertensive diastolic heart failure model rats
H Akahori, T Tsujino, Y Naito, M Matsumoto… - Journal of …, 2014 - journals.lww.com
Objective: Clinical studies have suggested the beneficial effects of statin therapy on diastolic
heart failure. However, the mechanism of the beneficial effects of statin on diastolic heart …
heart failure. However, the mechanism of the beneficial effects of statin on diastolic heart …
[HTML][HTML] Association between renal iron accumulation and renal interstitial fibrosis in a rat model of chronic kidney disease
Y Naito, A Fujii, H Sawada, M Oboshi, T Iwasaku… - Hypertension …, 2015 - nature.com
Iron accumulation is associated with the pathophysiology of chronic kidney disease (CKD).
Renal fibrosis is a final common feature that contributes to the progression of CKD; however …
Renal fibrosis is a final common feature that contributes to the progression of CKD; however …