Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine in humans
I Bjarnason, J Hayllar - Gastroenterology, 1993 - Elsevier
Background: It is not widely appreciated that nonsteroidal anti-inflammatory drugs (NSAIDs)
may cause damage distal to the duodenum. We reviewed the adverse effects of NSAIDs on …
may cause damage distal to the duodenum. We reviewed the adverse effects of NSAIDs on …
Intestinal permeability: an overview
I Bjarnason, A Macpherson, D Hollander - Gastroenterology, 1995 - Elsevier
The noninvasive assessment of intestinal permeability in humans has a 20-year history.
Because the tests are increasingly used in clinical practice and research and because there …
Because the tests are increasingly used in clinical practice and research and because there …
Mechanisms of damage to the gastrointestinal tract from nonsteroidal anti-inflammatory drugs
I Bjarnason, C Scarpignato, E Holmgren, M Olszewski… - Gastroenterology, 2018 - Elsevier
Nonsteroidal anti-inflammatory drugs (NSAIDs) can damage the gastrointestinal tract,
causing widespread morbidity and mortality. Although mechanisms of damage involve the …
causing widespread morbidity and mortality. Although mechanisms of damage involve the …
A simple method for assessing intestinal inflammation in Crohn's disease
…, R Foster, R Sherwood, M Fagerhol, I Bjarnason - Gut, 2000 - gut.bmj.com
BACKGROUND AND AIMS Assessing the presence and degree of intestinal inflammation
objectively, simply, and reliably is a significant problem in gastroenterology. We assessed …
objectively, simply, and reliably is a significant problem in gastroenterology. We assessed …
Mucosal antibodies in inflammatory bowel disease are directed against intestinal bacteria.
…, UY Khoo, I Forgacs, J Philpott-Howard, I Bjarnason - Gut, 1996 - gut.bmj.com
In contrast with normal subjects where IgA is the main immunoglobulin in the intestine,
patients with active inflammatory bowel disease (IBD) produce high concentrations of IgG …
patients with active inflammatory bowel disease (IBD) produce high concentrations of IgG …
Surrogate markers of intestinal inflammation are predictive of relapse in patients with inflammatory bowel disease
…, G Sigthorsson, S Bridger, MK Fagerhol, I Bjarnason - Gastroenterology, 2000 - Elsevier
Background & Aims: Prediction of relapse of inflammatory bowel disease has important
implications for therapeutic stategies. We assessed whether measurement of intestinal …
implications for therapeutic stategies. We assessed whether measurement of intestinal …
Reduced bone density in patients with inflammatory bowel disease.
I Bjarnason, A Macpherson, C Mackintosh… - Gut, 1997 - gut.bmj.com
BACKGROUND: Reduced bone mineral density in patients with inflammatory bowel disease
is thought to be due to disturbances in calcium homeostasis or the effects of corticosteroid …
is thought to be due to disturbances in calcium homeostasis or the effects of corticosteroid …
Use of surrogate markers of inflammation and Rome criteria to distinguish organic from nonorganic intestinal disease
…, G Sigthorsson, R Foster, I Forgacs, I Bjarnason - Gastroenterology, 2002 - Elsevier
Background & Aims: Differentiating symptoms of irritable bowel syndrome (IBS) from those of
organic intestinal disease is a familiar problem for physicians. The aim of this study was to …
organic intestinal disease is a familiar problem for physicians. The aim of this study was to …
A quantitative analysis of NSAID-induced small bowel pathology by capsule enteroscopy
…, B Thjodleifsson, A Theodors, J Gonzalez, I Bjarnason - Gastroenterology, 2005 - Elsevier
Background & Aims: Conventional acidic nonsteroidal anti-inflammatory drugs frequently
cause small bowel inflammation. Diagnosis is largely based on assay of surrogate markers …
cause small bowel inflammation. Diagnosis is largely based on assay of surrogate markers …
Long-term effects of nonsteroidal anti-inflammatory drugs and cyclooxygenase-2 selective agents on the small bowel: a cross-sectional capsule enteroscopy study
…, II Bjarnason, D Scott, S Birgisson, I Bjarnason - Clinical …, 2007 - Elsevier
Background & Aims: Nonsteroidal anti-inflammatory drug (NSAID) gastropathy is sufficiently
important as to warrant co-administration of misoprostol or proton pump inhibitors or a switch …
important as to warrant co-administration of misoprostol or proton pump inhibitors or a switch …