The contribution of platelets to the process of atherosclerosis remains unclear. Here, we
show in vivo that platelets adhere to the vascular endothelium of the carotid artery in …

Dual antiplatelet therapy with aspirin and clopidogrel decreases the rate of stent thrombosis
in patients undergoing percutaneous coronary intervention (PCI). However, despite …

Following coronary stent placement, platelet activation is a major determinant of the risk of
subacute stent thrombosis. 1 Combined antiplatelet treatment with ticlopidine and aspirin …

Abstract Organ-on-chip (OoC) technology is full of engineering and biological challenges,
but it has the potential to revolutionize the Next-Generation Risk Assessment of novel …

The γ‐amino butyric acid (GABA) synthetic enzyme glutamic acid decarboxylase (GAD) 65 is
critically involved in the activity‐dependent regulation of GABAergic inhibition in the central …

Platelet—collagen interactions play a fundamental role in the process of arterial thrombosis.
The major platelet collagen receptor is the glycoprotein VI (GPVI). Here, we determined the …

The mechanisms leading to prostate cancer metastasis are not understood completely.
Although there is evidence that the CXC chemokine receptor (CXCR) 4 and its ligand …

Background Maintenance of differentiation programs requires stability, when appropriate, of
transcriptional states. However, the extent to which inheritance of active transcriptional …

Aims Previous experimental studies have suggested that platelet stromal-cell-derived factor-
1 (SDF-1) regulates mobilization and recruitment of haematopoietic progenitor cells …

CRISPR interference (CRISPRi) represents a newly developed tool for targeted gene
repression. It has great application potential for studying gene function and mapping gene …