Defining new approaches for the prevention and treatment of atherosclerosis is an important
priority. Recently, measurement of endothelial function in patients has emerged as a useful …

This review focuses on the role of oxidative processes in atherosclerosis and its resultant
cardiovascular events. There is now a consensus that atherosclerosis represents a state of …

Epidemiologic studies have demonstrated an association between increased intake of
antioxidant vitamins such as vitamin E and vitamin C and reduced morbidity and mortality …

Objective—To determine the clinical conditions associated with systemic oxidative stress in
a community-based cohort. Information regarding cardiovascular risk factors associated with …

We have recently shown that nitric oxide or authentic endothelium-derived relaxing factor
generated in a biologic system reacts in the presence of specific protein thiols to form S …

Analysis of de novo CNVs (dnCNVs) from the full Simons Simplex Collection (SSC)(N=
2,591 families) replicates prior findings of strong association with autism spectrum disorders …

Background—Excess adiposity is associated with greater systemic inflammation. Whether
visceral adiposity is more proinflammatory than subcutaneous abdominal adiposity is …

Background—Brachial artery endothelial function is impaired in individuals with
atherosclerosis and coronary risk factors and improves with risk reduction therapy. However …

The endothelium regulates vascular homeostasis by elaborating a variety of paracrine
factors that act locally in the blood vessel wall and lumen. 1 Under normal conditions, the …

Objectives: The goal of this study was to prospectively examine the long-term predictive
value of brachial-artery endothelial dysfunction for future cardiovascular events …