Chronic inflammation might correlate with the formation of α-synuclein oligomers,
subsequently leading to dopaminergic (DA) neuronal death in Parkinson's disease (PD). As …

Autophagy involves degradation of dysfunctional cellular components through the actions of
lysosomes. Apoptosis is the process of programmed cell death involving a series of …

A pivotal neuropathological manifestation of synucleinopathies, like Parkinson's disease
(PD), is the aggregation of α-synuclein. In a recent cell-to-cell transmission model of α …

Ferroptosis, a novel form of regulated cell death, is caused by accumulation of lipid
peroxides and excessive iron deposition. This process has been linked to the death of …

The aim of this study was to confirm the utility of aerosolised iloprost for identifying long-term
responders to calcium channel blockers (CCBs) in patients with idiopathic pulmonary …

Recent evidence suggests that innate and adaptive immunity play a crucial role in
Parkinson's disease (PD). However, studies regarding specific immune cell classification in …

BACKGROUND: Although previous studies have shown that peripheral airway obstruction
can occur in idiopathic PAH (IPAH), pulmonary function tests have not been well-studied in …

Autophagy is an intracellular “self-eating” process that is closely related to inflammation and
cellular immunity. New studies indicate that autophagy is also involved in tumor …

The constitutive modeling of soil–structure interfaces plays a major role in numerical
simulation of soil–structure interaction problems. The interface shear tests showed that the …

Background Emerging evidence indicates that the apolipoprotein E (APOE) ε4 exacerbates
α‐synuclein pathology. Objective To determine whether APOE ε4 contributes to motor …