The Worcester Venous Thromboembolism study: a population‐based study of the clinical epidemiology of venous thromboembolism

FA Spencer, C Emery, D Lessard… - Journal of general …, 2006 - Wiley Online Library
BACKGROUND: While there have been marked advances in diagnostic and therapeutic
strategies for venous thromboembolism, our understanding of its clinical epidemiology is …

Correlates of echocardiographic indices of cardiac remodeling over the adult life course: longitudinal observations from the Framingham Heart Study

S Cheng, V Xanthakis, LM Sullivan, W Lieb… - Circulation, 2010 - Am Heart Assoc
Background—The heart progressively remodels over the life course, yet longitudinal data
characterizing such remodeling in the community are limited. Methods and Results—Using …

Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data

RS Vasan, NL Glazer, JF Felix, W Lieb, PS Wild… - Jama, 2009 - jamanetwork.com
Context Echocardiographic measures of left ventricular (LV) structure and function are
heritable phenotypes of cardiovascular disease. Objective To identify common genetic …

Longitudinal tracking of left ventricular mass over the adult life course: clinical correlates of short-and long-term change in the framingham offspring study

W Lieb, V Xanthakis, LM Sullivan, J Aragam… - Circulation, 2009 - Am Heart Assoc
Background—Information is limited on the longitudinal tracking of left ventricular (LV) mass
over the adult life course and the determinants of such change. Methods and Results—We …

Epidemiology of left ventricular systolic dysfunction and heart failure in the Framingham study: an echocardiographic study over 3 decades

RS Vasan, V Xanthakis, A Lyass, C Andersson… - JACC: Cardiovascular …, 2018 - jacc.org
Objectives: The purpose of this study was to describe the temporal trends in prevalence of
left ventricular systolic dysfunction (LVSD) in individuals without and with heart failure (HF) …

Aortic root remodeling over the adult life course: longitudinal data from the Framingham Heart Study

CSP Lam, V Xanthakis, LM Sullivan, W Lieb… - Circulation, 2010 - Am Heart Assoc
Background—Aortic root remodeling in adulthood is known to be associated with
cardiovascular outcomes. However, there is a lack of longitudinal data defining the clinical …

The natural history of left ventricular geometry in the community: clinical correlates and prognostic significance of change in LV geometric pattern

W Lieb, P Gona, MG Larson, J Aragam, MR Zile… - JACC: Cardiovascular …, 2014 - jacc.org
Objectives: This study sought to evaluate pattern and clinical correlates of change in left
ventricular (LV) geometry over a 4-year period in the community; it also assessed whether …

Left ventricular hypertrophy patterns and incidence of heart failure with preserved versus reduced ejection fraction

RS Velagaleti, P Gona, MJ Pencina, J Aragam… - The American journal of …, 2014 - Elsevier
Higher left ventricular (LV) mass, wall thickness, and internal dimension are associated with
increased heart failure (HF) risk. Whether different LV hypertrophy patterns vary with respect …

Role of myocardial strain imaging in surveillance and management of cancer therapeutics‐related cardiac dysfunction: a systematic review

PC McGregor, FA Moura, J Banchs… - …, 2021 - Wiley Online Library
Transthoracic echocardiography is the primary cardiac imaging modality for the detection of
Cancer Therapeutics‐Related Cardiac Dysfunction (CTRCD) through evaluation of serial …

Age-and sex-based reference limits and clinical correlates of myocardial strain and synchrony: the Framingham Heart Study

S Cheng, MG Larson, EL McCabe… - Circulation …, 2013 - Am Heart Assoc
Background—There is rapidly growing interest in applying measures of myocardial strain
and synchrony in clinical investigations and in practice; data are limited regarding their …