User profiles for "author:James H Park"

James H. Park

- Verified email at glasgow.ac.uk - Cited by 2507

James H. Park

- Verified email at post.harvard.edu - Cited by 1169

James H. Park

- Verified email at isbscience.org - Cited by 232

[PDF][PDF] Nogo-66 receptor prevents raphespinal and rubrospinal axon regeneration and limits functional recovery from spinal cord injury

JE Kim, BP Liu, JH Park, SM Strittmatter - Neuron, 2004 - cell.com
Axon regeneration after injury to the adult mammalian CNS is limited in part by three
inhibitory proteins in CNS myelin: Nogo-A, MAG, and OMgp. All three of these proteins bind …

[HTML][HTML] The local inflammatory response in colorectal cancer–type, location or density? A systematic review and meta-analysis

PG Alexander, DC McMillan, JH Park - Cancer treatment reviews, 2020 - Elsevier
Introduction The host anti-tumour inflammatory response is a strong prognostic indicator,
and tumour infiltrating lymphocytes (TILs) are believed to have a complimentary role …

[HTML][HTML] A systems approach to brain tumor treatment

JH Park, ALG de Lomana, DM Marzese, T Juarez… - Cancers, 2021 - mdpi.com
Simple Summary Pronounced differences across individuals (interpatient variability) and cell–
cell heterogeneity within a tumor (intratumoral heterogeneity) severely hinder effective brain …

The tubulin code in neuronal polarity

JH Park, A Roll-Mecak - Current opinion in neurobiology, 2018 - Elsevier
Highlights•Isoforms and posttranslational modifications generate the tubulin code for
neuronal polarization.•Tubulin isoforms have distinct properties and functions.•Tubulin …

Colorectal cancer, systemic inflammation, and outcome: staging the tumor and staging the host

JH Park, DG Watt, CSD Roxburgh, PG Horgan… - Annals of …, 2016 - journals.lww.com
Objective: This study aims to examine the clinical utility of the combination of TNM stage and
modified Glasgow Prognostic Score (mGPS) in patients undergoing potentially curative …

Alzheimer precursor protein interaction with the Nogo-66 receptor reduces amyloid-β plaque deposition

JH Park, DA Gimbel, T GrandPre, JK Lee… - Journal of …, 2006 - Soc Neuroscience
Pathophysiologic hypotheses for Alzheimer's disease (AD) are centered on the role of the
amyloid plaque Aβ peptide and the mechanism of its derivation from the amyloid precursor …

Staphylococcus aureus pneumonia

HT Chickering, JH Park - Journal of the American Medical …, 1919 - jamanetwork.com
In the standard textbooks the staphylococcus is usually noted among other micro-organisms
as a possible etiologic agent in the production of bronchopneumonia. A detailed description …

Potentially detrimental cardiovascular effects of oxygen in patients with chronic left ventricular systolic dysfunction

JH Park, S Balmain, C Berry, JJ Morton, JJV McMurray - Heart, 2010 - heart.bmj.com
Background Although the haemodynamic effects of oxygen in healthy subjects are well
documented, there have been no well-controlled studies of the effects of oxygen in patients …

[HTML][HTML] The prognostic value of systemic inflammation in patients undergoing surgery for colon cancer: comparison of composite ratios and cumulative scores

RD Dolan, ST McSorley, JH Park, DG Watt… - British journal of …, 2018 - nature.com
Introduction The systemic inflammatory response has been proven to have a prognostic
value. There are two methods of assessing the systemic inflammatory response composite …

Loss of RPGR glutamylation underlies the pathogenic mechanism of retinal dystrophy caused by TTLL5 mutations

X Sun, JH Park, J Gumerson, Z Wu… - Proceedings of the …, 2016 - National Acad Sciences
Mutations in the X-linked retinitis pigmentosa GTPase regulator (RPGR) gene are a major
cause of retinitis pigmentosa, a blinding retinal disease resulting from photoreceptor …