BACKGROUND: Clozapine is the drug of choice for patients with unsatisfactory response to
routine antipsychotic treatment. Polypharmacy is widely used among patients having …

Abstract Changes over 50 years of research on antipsychotics in schizophrenia have
occurred. A scientometric synthesis of such changes over time and a measure of …

OBJECTIVE: To evaluate the efficacy of glutamatergic drugs, acting agonistically on the N-
methyl-d-aspartate (NMDA) or the non-NMDA receptors, in schizophrenia. METHOD: All …

Background The introduction of second-generation antipsychotic drugs during the 1990s is
widely believed to have adversely affected mortality of patients with schizophrenia. Our aim …

Objective: Data on the effectiveness of antipsychotics in the early phase of schizophrenia
are limited. The authors examined the risk of rehospitalization and drug discontinuation in a …

Objective To study the association between prescribed antipsychotic drugs and outcome in
schizophrenia or schizoaffective disorder in the community. Design Prospective cohort study …

Importance The effectiveness of antipsychotic polypharmacy in schizophrenia relapse
prevention is controversial, and use of multiple agents is generally believed to impair …

Importance It has remained unclear whether there are clinically meaningful differences
between antipsychotic treatments with regard to preventing relapse of schizophrenia, owing …

Objective: It is generally believed that after the first episode of schizophrenia, the risk of
relapse decreases with time in patients who are stabilized. Many treatment guidelines …

O bjective: The purpose of the study was to examine the quantitative risk of criminal behavior
associated with specific mental disorders. Method: An unselected 1966 birth cohort (N …