Cardiac amyloidosis of transthyretin fibril protein (ATTR) type is an infiltrative
cardiomyopathy characterised by ventricular wall thickening and diastolic heart failure …

Background Patients with dilated cardiomyopathy whose symptoms and cardiac function
have recovered often ask whether their medications can be stopped. The safety of …

Background: The p. Val142Ile variant, predominantly found among people of African
descent, is the most common cause of variant transthyretin amyloidosis and carriers …

Background Percutaneous coronary intervention (PCI) is frequently performed to reduce the
symptoms of stable angina. Whether PCI relieves angina more than a placebo procedure in …

Background Cardiac amyloidosis is a fatal disease whose prognosis and treatment rely on
identification of the amyloid type. In our aging population transthyretin amyloidosis (ATTR …

Objectives: This study was devised to describe the different cardiac magnetic resonance
(CMR) appearances in light chain amyloid (AL) and transthyretin-related amyloidosis …

Epidemiological studies of systemic amyloidosis are scarce and the burden of disease in E
ngland has not previously been estimated. In 1999, the N ational H ealth S ervice …

Background—It has been reported that subjects of African descent present with heart failure
at a younger age and because of different causes than whites. We present contemporary …

BACKGROUND: About 4% of African Americans possess the isoleucine 122 (V122I) variant
of transthyretin, associated with cardiac amyloidosis beyond ages of 55 to 60 years …

Aims There is an important need for better biomarkers to predict left ventricular (LV)
remodelling in dilated cardiomyopathy (DCM). We undertook a comprehensive assessment …