User profiles for "author:Julian Gillmore"
Julian GillmoreUCL Verified email at ucl.ac.uk Cited by 30569 |
Systemic amyloidosis
Tissue deposition of protein fibrils causes a group of rare diseases called systemic
amyloidoses. This Seminar focuses on changes in their epidemiology, the current approach …
amyloidoses. This Seminar focuses on changes in their epidemiology, the current approach …
ASNC/AHA/ASE/EANM/HFSA/ISA/SCMR/SNMMI expert consensus recommendations for multimodality imaging in cardiac amyloidosis: part 1 of 2—evidence base …
S Dorbala, Y Ando, S Bokhari, A Dispenzieri… - Journal of Nuclear …, 2019 - Springer
Cardiac amyloidosis is a form of restrictive infiltrative cardiomyopathy that confers significant
mortality. Due to the relative rarity of cardiac amyloidosis, clinical and diagnostic expertise in …
mortality. Due to the relative rarity of cardiac amyloidosis, clinical and diagnostic expertise in …
[HTML][HTML] The evaluation of monoclonal gammopathy of renal significance: a consensus report of the International Kidney and Monoclonal Gammopathy Research …
The term monoclonal gammopathy of renal significance (MGRS) was introduced by the
International Kidney and Monoclonal Gammopathy Research Group (IKMG) in 2012. The …
International Kidney and Monoclonal Gammopathy Research Group (IKMG) in 2012. The …
[HTML][HTML] CRISPR-Cas9 in vivo gene editing for transthyretin amyloidosis
JD Gillmore, E Gane, J Taubel, J Kao… - … England Journal of …, 2021 - Mass Medical Soc
Background Transthyretin amyloidosis, also called ATTR amyloidosis, is a life-threatening
disease characterized by progressive accumulation of misfolded transthyretin (TTR) protein …
disease characterized by progressive accumulation of misfolded transthyretin (TTR) protein …
Nonbiopsy diagnosis of cardiac transthyretin amyloidosis
Background—Cardiac transthyretin (ATTR) amyloidosis is a progressive and fatal
cardiomyopathy for which several promising therapies are in development. The diagnosis is …
cardiomyopathy for which several promising therapies are in development. The diagnosis is …
Diagnosis and treatment of cardiac amyloidosis: a position statement of the ESC Working Group on Myocardial and Pericardial Diseases
P Garcia-Pavia, C Rapezzi, Y Adler, M Arad… - European heart …, 2021 - academic.oup.com
Cardiac amyloidosis is a serious and progressive infiltrative disease that is caused by the
deposition of amyloid fibrils at the cardiac level. It can be due to rare genetic variants in the …
deposition of amyloid fibrils at the cardiac level. It can be due to rare genetic variants in the …
[HTML][HTML] Natural history and outcome in systemic AA amyloidosis
HJ Lachmann, HJB Goodman… - … England Journal of …, 2007 - Mass Medical Soc
Background Deposition of amyloid fibrils derived from circulating acute-phase reactant
serum amyloid A protein (SAA) causes systemic AA amyloidosis, a serious complication of …
serum amyloid A protein (SAA) causes systemic AA amyloidosis, a serious complication of …
[HTML][HTML] Misdiagnosis of hereditary amyloidosis as AL (primary) amyloidosis
Background Hereditary, autosomal dominant amyloidosis, caused by mutations in the genes
encoding transthyretin, fibrinogen A α-chain, lysozyme, or apolipoprotein AI, is thought to be …
encoding transthyretin, fibrinogen A α-chain, lysozyme, or apolipoprotein AI, is thought to be …
Amyloid load and clinical outcome in AA amyloidosis in relation to circulating concentration of serum amyloid A protein
Background Reactive systemic (AA, secondary) amyloidosis occurs in chronic inflammatory
diseases, and most patients present with nephropathy. The amyloid fibrils are derived from …
diseases, and most patients present with nephropathy. The amyloid fibrils are derived from …
Prognostic value of late gadolinium enhancement cardiovascular magnetic resonance in cardiac amyloidosis
M Fontana, S Pica, P Reant, A Abdel-Gadir, TA Treibel… - Circulation, 2015 - Am Heart Assoc
Background—The prognosis and treatment of the 2 main types of cardiac amyloidosis,
immunoglobulin light chain (AL) and transthyretin (ATTR) amyloidosis, are substantially …
immunoglobulin light chain (AL) and transthyretin (ATTR) amyloidosis, are substantially …