Background Comparable data on the global and country-specific burden of neurological
disorders and their trends are crucial for health-care planning and resource allocation. The …

Importance The increasing burden due to cancer and other noncommunicable diseases
poses a threat to human development, which has resulted in global political commitments …

Objective. To provide a state of the art of economic analyses applied to rheumatoid arthritis
(RA). Methods. A systematic literature review on economic consequences and …

Background—Nonadherence to antihypertensive treatment is a common problem in
cardiovascular prevention and may influence prognosis. We explored predictors of …

Background Limited data are available on the characteristics, clinical management, and
outcomes of patients with atrial fibrillation at risk of stroke, from a worldwide perspective. The …

Inhibitors in patients with hemophilia are a rare complication of a rare disease causing pain
and disability in patients and impairment to the quality of their lives. Recent advances in …

BACKGROUND: Atrial fibrillation (AF) is associated with high rates of morbidity and
mortality. Patients with AF carry a fivefold increased risk of stroke and the risk of death from …

Aims The relationship between outcomes and time after diagnosis for patients with non-
valvular atrial fibrillation (NVAF) is poorly defined, especially beyond the first year. Methods …

Objective We studied evolving antithrombotic therapy patterns in patients with newly
diagnosed non-valvular atrial fibrillation (AF) and≥ 1 additional stroke risk factor between …

Background The efficacy and safety of the anticoagulant rivaroxaban for the treatment and
secondary prevention of deep-vein thrombosis and pulmonary embolism has been shown in …