Perioperative myocardial injury after noncardiac surgery: incidence, mortality, and characterization

C Puelacher, G Lurati Buse, D Seeberger, L Sazgary… - Circulation, 2018 - Am Heart Assoc
Background: Perioperative myocardial injury (PMI) seems to be a contributor to mortality
after noncardiac surgery. Because the vast majority of PMIs are asymptomatic, PMI usually is …

0/1-Hour triage algorithm for myocardial infarction in patients with renal dysfunction

R Twerenbold, P Badertscher, J Boeddinghaus… - Circulation, 2018 - Am Heart Assoc
Background: The European Society of Cardiology recommends a 0/1-hour algorithm for
rapid rule-out and rule-in of non–ST-segment elevation myocardial infarction using high …

Effect of definition on incidence and prognosis of type 2 myocardial infarction

T Nestelberger, J Boeddinghaus, P Badertscher… - Journal of the American …, 2017 - jacc.org
Background: Uncertainties regarding the most appropriate definition and treatment of type 2
myocardial infarction (T2MI) due to supply-demand mismatch have contributed to …

Incidence of major adverse cardiac events following non-cardiac surgery

L Sazgary, C Puelacher, G Lurati Buse… - … Heart Journal Acute …, 2021 - academic.oup.com
Aims Major adverse cardiac events (MACE) triggered by non-cardiac surgery are
prognostically important perioperative complications. However, due to often asymptomatic …

Incidence and outcomes of unstable angina compared with non-ST-elevation myocardial infarction

C Puelacher, M Gugala, PD Adamson, A Shah… - Heart, 2019 - heart.bmj.com
Objective Assess the relative incidence and compare characteristics and outcome of
unstable angina (UA) and non-ST-elevation myocardial infarction (NSTEMI). Design Two …

Direct comparison of the 0/1h and 0/3h algorithms for early rule-out of acute myocardial infarction

P Badertscher, J Boeddinghaus, R Twerenbold… - Circulation, 2018 - Am Heart Assoc
0.13 [95% CI, 0.09–0.19]) and allowed the rule-out of a similar portion of patients compared
with the 0/3halgorithm (52% versus 51%; P= 0.507; Figure). Overall, 711 patients (28%) …

Comparison of fourteen rule-out strategies for acute myocardial infarction

K Wildi, J Boeddinghaus, T Nestelberger… - International journal of …, 2019 - Elsevier
Background The clinical availability of high-sensitivity cardiac troponin (hs-cTn) has enabled
the development of several innovative strategies for the rapid rule-out of acute myocardial …

Comparison of high-sensitivity cardiac troponin I and T for the prediction of cardiac complications after non-cardiac surgery

DM Gualandro, C Puelacher, G LuratiBuse… - American heart …, 2018 - Elsevier
Background We aimed to directly compare preoperative high-sensitivity cardiac troponin (hs-
cTn) I and T concentration for the prediction of major cardiac complications after non-cardiac …

Prospective validation of a biomarker-based rule out strategy for functionally relevant coronary artery disease

JE Walter, U Honegger, C Puelacher… - Clinical …, 2018 - academic.oup.com
BACKGROUND This study aimed to prospectively advance a rule-out strategy for
functionally significant coronary artery disease (CAD) by use of high-sensitivity cardiac …

Incremental diagnostic and prognostic value of the QRS-T angle, a 12-lead ECG marker quantifying heterogeneity of depolarization and repolarization, in patients with …

I Strebel, R Twerenbold, D Wussler… - International journal of …, 2019 - Elsevier
Background The value of the 12-lead ECG in the diagnosis of non-ST-elevation myocardial
infarction (NSTEMI) is limited due to insufficient sensitivity and specificity of standard ECG …