The historical view of vascular smooth muscle cells (VSMCs) in atherosclerosis is that
aberrant proliferation of VSMCs promotes plaque formation, but that VSMCs in advanced …

Vascular smooth muscle cells (VSMCs) are a major cell type present at all stages of an
atherosclerotic plaque. According to the 'response to injury'and 'vulnerable …

Importance The incidence of early-onset colorectal cancer (younger than 50 years) is rising
globally, the reasons for which are unclear. It appears to represent a unique disease …

The second edition of the seminal work in the field—revised, updated, and extended In
Philosophical Foundations of Neuroscience, MR Bennett and PMS Hacker outline and …

One defining goal of synthetic biology is the development of engineering-based approaches
that enable the construction of gene-regulatory networks according to 'design specifications' …

The mechanisms involved in the initiation of vascular calcification are not known, but matrix
vesicles, the nucleation sites for calcium crystal formation in bone, are likely candidates …

Vascular smooth muscle cell (VSMC) apoptosis occurs in many arterial diseases, including
aneurysm formation, angioplasty restenosis and atherosclerosis. Although VSMC apoptosis …

Objectives: The purpose of this study was to determine whether thin-capped fibroatheromata
(TCFA) identified by virtual histology intravascular ultrasound (VH-IVUS) are associated with …

We have investigated the mechanism by which deregulated expression of c‐Myc induces
death by apoptosis in serum‐deprived fibroblasts. We demonstrate that Myc‐induced …

Vascular calcification is a complex biological process that is a hallmark of atherosclerosis.
While macrocalcification confers plaque stability, microcalcification is a key feature of high …