Objectives Vitamin D insufficiency has been linked to hypertension and cardiovascular
events in observational studies. It is unclear whether vitamin D supplementation can reduce …

Allopurinol ameliorates endothelial dysfunction and arterial stiffness among patients without
chronic kidney disease (CKD), but it is unknown if it has similar effects among patients with …

Vitamin D has been known to medical science for almost a century. Yet, it is only in the last
15 years that we have realized that the biological effects of vitamin D extend far beyond the …

Objectives: The purpose of this study was to investigate the impact of renin-angiotensin
system blockade therapy on outcomes in aortic stenosis (AS). Background: Angiotensin …

Objectives: This study sought to ascertain if high-dose allopurinol regresses left ventricular
mass (LVM) in patients with ischemic heart disease (IHD). Background: LV hypertrophy …

Studies in victims of sudden cardiac death and those surviving a cardiac arrest have
confirmed that extent of coronary artery disease is similar in those with and without angina …

Objectives: The aim of this study was to examine whether biomarkers can identify silent
cardiac target organ damage (cTOD) in a primary prevention population. Background: One …

Mitral regurgitation (MR) following acute myocardial infarction (AMI) worsens prognosis and
reports of prevalence vary significantly. The objective was to determine prevalence, risk …

Transcatheter aortic valve replacement (TAVR) is increasingly being performed to treat
symptomatic patients with aortic stenosis and annual procedure volume has overtaken …

Objectives: The purpose of this study was to identify the relationship of B-type natriuretic
peptide (BNP) with evolution of left ventricular mass (LVM) in optimally treated primary …