[HTML][HTML] Acute therapy of newborns with critical congenital heart disease

M Khalil, C Jux, L Rueblinger, J Behrje… - Translational …, 2019 - ncbi.nlm.nih.gov
Critical congenital heart disease (cCHD) is the most common reason for acute cardiac
failure in the neonatal period. cCHD, defined by systemic low cardiac output (LCO) and …

Comparison of contractile behavior of native murine ventricular tissue and cardiomyocytes derived from embryonic or induced pluripotent stem cells

J Xi, M Khalil, N Shishechian, T Hannes… - The FASEB …, 2010 - Wiley Online Library
Cardiomyocytes generated from embryonic stem cells (ESCs) and induced pluripotent stem
(iPS) cells are suggested for repopulation of destroyed myocardium. Because contractile …

Contractile properties of early human embryonic stem cell-derived cardiomyocytes: beta-adrenergic stimulation induces positive chronotropy and lusitropy but not …

F Pillekamp, M Haustein, M Khalil… - Stem cells and …, 2012 - liebertpub.com
Human embryonic stem cell-derived cardiomyocytes (hESC-CMs) provide the unique
opportunity to study the very early development of the human heart. The aim of this study …

Towards a proposal for a universal diagnostic definition of protein-losing enteropathy in Fontan patients: a systematic review

FEU Ten Cate, T Hannes, I Germund, M Khalil… - Heart, 2016 - heart.bmj.com
Objective A standardised diagnostic definition of protein-losing enteropathy (PLE) in Fontan
patients serves both patient care and research. The present study determined whether a …

Severe heart failure and the need for mechanical circulatory support and heart transplantation in pediatric patients with myocarditis: results from the prospective …

S Schubert, B Opgen‐Rhein, M Boehne… - Pediatric …, 2019 - Wiley Online Library
Myocarditis represents an important cause for acute heart failure. MYKKE, a prospective
multicenter registry of pediatric patients with myocarditis, aims to gain knowledge on …

The influence of physiological matrix conditions on permanent culture of induced pluripotent stem cell-derived cardiomyocytes

CO Heras-Bautista, A Katsen-Globa, NE Schloerer… - Biomaterials, 2014 - Elsevier
Cardiomyocytes (CMs) from induced pluripotent stem (iPS) cells mark an important
achievement in the development of in vitro pharmacological, toxicological and …

Integration properties of Wharton's jelly-derived novel mesenchymal stem cells into ventricular slices of murine hearts

M Lupu, M Khalil, E Andrei, F Iordache… - Cellular Physiology and …, 2011 - karger.com
Wharton's jelly (WJ) is a rich source of multiple-lineage differentiating cells, recently
proposed for cell replacement therapy. However, their ability to integrate into the cardiac …

Toward evidence-based diagnosis of myocarditis in children and adolescents: Rationale, design, and first baseline data of MYKKE, a multicenter registry and study …

DR Messroghli, T Pickardt, M Fischer… - American Heart …, 2017 - Elsevier
Aims The aim of this registry is to provide data on age-related clinical features of suspected
myocarditis and to create a study platform allowing for deriving diagnostic criteria and, at a …

Impact of residual right ventricular outflow tract obstruction on biventricular strain and synchrony in patients after repair of tetralogy of Fallot: a cardiac magnetic …

H Latus, P Hachmann, K Gummel… - European Journal of …, 2015 - academic.oup.com
OBJECTIVES Residual right ventricular outflow tract (RVOT) obstruction (RVOTO) is
considered beneficial in patients after repair of tetralogy of Fallot (TOF) although underlying …

[HTML][HTML] Focal myocardial fibrosis assessed by late gadolinium enhancement cardiovascular magnetic resonance in children and adolescents with dilated …

H Latus, K Gummel, K Klingel, A Moysich… - Journal of …, 2015 - Elsevier
Background Different patterns of late gadolinium enhancement (LGE) including mid-wall
fibrosis using cardiovascular magnetic resonance (CMR) have been reported in adult …