Background and Purpose—Dabigatran-etexilate (DE) recently has been approved for stroke
prevention in atrial fibrillation. However, lack of effective antagonists represents a major …

Free radicals are involved in pathophysiology of ischemia/reperfusion injury (IRI). Melatonin
is a potent scavenger of reactive oxygen and nitrogen species. Thus, this study was …

Cardiac troponin (cTn) is a regulatory protein of the myofibrillar thin filament of striated
muscle regulating excitation–contraction coupling in the heart. w1 Among the three subunits …

Background and Purpose—Therapeutic modification of the postischemic immune processes
is a key target of current experimental stroke research. For successful translation into the …

Experimental data suggest that melatonin decreases inflammatory changes after major liver
resection, thus positively influencing the postoperative course. To assess the safety of a …

Infectious complications are the leading cause of death in the post-acute phase of stroke.
Post-stroke immunodeficiency is believed to result from neurohormonal dysregulation of the …

Background and Purpose—Rivaroxaban has recently been approved for stroke prevention
in atrial fibrillation. However, lack of an effective antidote represents a major concern in the …

Background The contribution of neuroinflammation and specifically brain lymphocyte
invasion is increasingly recognised as a substantial pathophysiological mechanism after …

Abstract Treatment with oral melphalan and dexamethasone (M-Dex) was reported to be
effective and feasible in patients with systemic light chain amyloidosis (AL) not eligible for …

Background Post-stroke immune depression contributes to the development of infections
which are major complications after stroke. Previous experimental and clinical studies …