User profiles for "author:Martin den Heijer"
Martin den HeijerAmsterdam UMC Verified email at amsterdamumc.nl Cited by 53699 |
Neural tube defects and folate: case far from closed
HJ Blom, GM Shaw, M Den Heijer… - Nature Reviews …, 2006 - nature.com
Neural tube closure takes place during early embryogenesis and requires interactions
between genetic and environmental factors. Failure of neural tube closure is a common …
between genetic and environmental factors. Failure of neural tube closure is a common …
Retinal vein occlusion: a form of venous thrombosis or a complication of atherosclerosis?
MCH Janssen, M den Heijer… - Thrombosis and …, 2005 - thieme-connect.com
Previous studies have shown an increased risk of retinal vein occlusion (RVO) in patients
with hypertension, hypercholesterolemia and diabetes mellitus. Literature on the association …
with hypertension, hypercholesterolemia and diabetes mellitus. Literature on the association …
Homocysteine, methylenetetrahydrofolate reductase and risk of schizophrenia: a meta-analysis
JW Muntjewerff, RS Kahn, HJ Blom… - Molecular psychiatry, 2006 - nature.com
Elevated plasma homocysteine concentration has been suggested as a risk factor for
schizophrenia, but the results of epidemiological studies have been inconsistent. The most …
schizophrenia, but the results of epidemiological studies have been inconsistent. The most …
Sequence variants at CHRNB3–CHRNA6 and CYP2A6 affect smoking behavior
TE Thorgeirsson, DF Gudbjartsson, I Surakka… - Nature …, 2010 - nature.com
Smoking is a common risk factor for many diseases. We conducted genome-wide
association meta-analyses for the number of cigarettes smoked per day (CPD) in smokers …
association meta-analyses for the number of cigarettes smoked per day (CPD) in smokers …
[HTML][HTML] Hyperhomocysteinemia as a risk factor for deep-vein thrombosis
M Den Heijer, T Koster, HJ Blom… - New England journal …, 1996 - Mass Medical Soc
Background Previous studies have suggested that hyperhomocysteinemia may be a risk
factor for venous thrombosis. To assess the risk of venous thrombosis associated with …
factor for venous thrombosis. To assess the risk of venous thrombosis associated with …
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
EK Speliotes, CJ Willer, SI Berndt, KL Monda… - Nature …, 2010 - nature.com
Obesity is globally prevalent and highly heritable, but its underlying genetic factors remain
largely elusive. To identify genetic loci for obesity susceptibility, we examined associations …
largely elusive. To identify genetic loci for obesity susceptibility, we examined associations …
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
Approaches exploiting trait distribution extremes may be used to identify loci associated with
common traits, but it is unknown whether these loci are generalizable to the broader …
common traits, but it is unknown whether these loci are generalizable to the broader …
Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for …
LA Kluijtmans, LP Van den Heuvel… - American Journal of …, 1996 - ncbi.nlm.nih.gov
Mild hyperhomocysteinemia is an established risk factor for cardiovascular disease. Genetic
aberrations in the cystathionine beta-synthase (CBS) and methylenetetrahydrofolate …
aberrations in the cystathionine beta-synthase (CBS) and methylenetetrahydrofolate …
[HTML][HTML] Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits
Given the anthropometric differences between men and women and previous evidence of
sex-difference in genetic effects, we conducted a genome-wide search for sexually …
sex-difference in genetic effects, we conducted a genome-wide search for sexually …
[HTML][HTML] Risk HLA-DQA1 and PLA2R1 Alleles in Idiopathic Membranous Nephropathy
HC Stanescu, M Arcos-Burgos, A Medlar… - … England Journal of …, 2011 - Mass Medical Soc
Background Idiopathic membranous nephropathy is a major cause of the nephrotic
syndrome in adults, but its etiologic basis is not fully understood. We investigated the genetic …
syndrome in adults, but its etiologic basis is not fully understood. We investigated the genetic …