Dysfunctional endothelium plays a crucial role in all stages of atherosclerosis and thus the
accurate assessment of this organ is a valuable tool, especially if such assessments are …

BACKGROUND: The benefits of adjunctive mechanical devices to prevent distal
embolization in patients with acute myocardial infarction (AMI) are still a matter of debate …

There is evidence that reactive oxygen species (ROS) are related to the development of
cardiovascular disease (CVD). Results from many studies support the hypothesis that ROS …

Previous in vitro studies have shown that isolated mitochondria can generate oxygen
radicals. However, whether a similar phenomenon can also occur in intact organs is …

Background—Endothelial dysfunction plays a key role in atherogenesis. We prospectively
investigated the impact of noninvasive measurement of endothelial function on …

Background Despite its limitations, unfractionated heparin has been the standard
anticoagulant used during percutaneous coronary intervention (PCI). Several small studies …

Background. Studies in animals have shown that serotonin constricts coronary arteries if the
endothelium is damaged, but in vitro studies have revealed a vasodilating effect on isolated …

Background The remodeling of the left ventricle in patients with aortic stenosis after aortic
valve replacement (AVR) is a complex process involving structural and functional changes …

Indirect evidence suggests that oxygen radicals may contribute to ischemic preconditioning.
We directly investigated whether exposure to oxygen radicals per se, in the absence of …

Objectives: The purpose of this study was to verify whether intima-media thickness (IMT)
regression is associated with reduced incidence of cardiovascular events. Background …