[HTML][HTML] Definition, classification and diagnosis of diabetes mellitus
A Petersmann, D Müller-Wieland… - Experimental and …, 2019 - thieme-connect.com
The recommended diagnostic procedure is shown in▶ Fig. 1. The differential diagnostic
criteria for type 1 diabetes and type 2 diabetes are listed in▶ Table 1. The criteria for the …
criteria for type 1 diabetes and type 2 diabetes are listed in▶ Table 1. The criteria for the …
Methods for measurement of LDL-cholesterol: a critical assessment of direct measurement by homogeneous assays versus calculation
M Nauck, GR Warnick, N Rifai - Clinical chemistry, 2002 - academic.oup.com
Abstract Background: Because LDL-cholesterol (LDL-C) is a modifiable risk for coronary
heart disease, its routine measurement is recommended in the evaluation and management …
heart disease, its routine measurement is recommended in the evaluation and management …
Evolution of methods for measurement of HDL-cholesterol: from ultracentrifugation to homogeneous assays
GR Warnick, M Nauck, N Rifai - Clinical chemistry, 2001 - academic.oup.com
Background: Adoption of automated homogeneous assays for HDL-cholesterol (HDL-C) is
increasing, driven by the need of clinical laboratories to cope with increasing workloads …
increasing, driven by the need of clinical laboratories to cope with increasing workloads …
Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression
Trait-associated genetic variants affect complex phenotypes primarily via regulatory
mechanisms on the transcriptome. To investigate the genetics of gene expression, we …
mechanisms on the transcriptome. To investigate the genetics of gene expression, we …
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
Major depressive disorder (MDD) is a common illness accompanied by considerable
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …
Cohort profile: the study of health in Pomerania
H Völzke, D Alte, CO Schmidt, D Radke… - International journal …, 2011 - academic.oup.com
Although in the past century mortality in West Germany decreased similarly as in other
Western nations, these changes were less pronounced in East Germany. 1, 2 After German …
Western nations, these changes were less pronounced in East Germany. 1, 2 After German …
Systematic identification of trans eQTLs as putative drivers of known disease associations
Identifying the downstream effects of disease-associated SNPs is challenging. To help
overcome this problem, we performed expression quantitative trait locus (eQTL) meta …
overcome this problem, we performed expression quantitative trait locus (eQTL) meta …
New loci associated with kidney function and chronic kidney disease
A Köttgen, C Pattaro, CA Böger, C Fuchsberger… - Nature …, 2010 - nature.com
Chronic kidney disease (CKD) is a significant public health problem, and recent genetic
studies have identified common CKD susceptibility variants. The CKDGen consortium …
studies have identified common CKD susceptibility variants. The CKDGen consortium …
[HTML][HTML] Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations
Elevated serum uric acid levels cause gout and are a risk factor for cardiovascular disease
and diabetes. To investigate the polygenetic basis of serum uric acid levels, we conducted a …
and diabetes. To investigate the polygenetic basis of serum uric acid levels, we conducted a …
Identification of common variants associated with human hippocampal and intracranial volumes
Identifying genetic variants influencing human brain structures may reveal new biological
mechanisms underlying cognition and neuropsychiatric illness. The volume of the …
mechanisms underlying cognition and neuropsychiatric illness. The volume of the …