User profiles for "author:Miao Wang"

Miao Wang

Sanford Burnham Prebys Medical Discovery Institute
Verified email at sbpdiscovery.org
Cited by 3579

Protein misfolding in the endoplasmic reticulum as a conduit to human disease

M Wang, RJ Kaufman - Nature, 2016 - nature.com
In eukaryotic cells, the endoplasmic reticulum is essential for the folding and trafficking of
proteins that enter the secretory pathway. Environmental insults or increased protein …

The impact of the endoplasmic reticulum protein-folding environment on cancer development

M Wang, RJ Kaufman - Nature Reviews Cancer, 2014 - nature.com
The endoplasmic reticulum (ER) is an essential organelle in eukaryotic cells for the storage
and regulated release of calcium and as the entrance to the secretory pathway. Protein …

Epidemiology of cardiovascular disease in China: current features and implications

D Zhao, J Liu, M Wang, X Zhang, M Zhou - Nature Reviews Cardiology, 2019 - nature.com
Cardiovascular disease (CVD) is the leading cause of death in China. To develop effective
and timely strategies to cope with the challenges of CVD epidemics, we need to understand …

Robust memristors based on layered two-dimensional materials

M Wang, S Cai, C Pan, C Wang, X Lian, Y Zhuo… - Nature …, 2018 - nature.com
Van der Waals heterostructures are formed by stacking layers of different two-dimensional
materials and offer the possibility to design new materials with atomic-level precision. By …

[HTML][HTML] Genomic variation in 3,010 diverse accessions of Asian cultivated rice

W Wang, R Mauleon, Z Hu, D Chebotarov, S Tai, Z Wu… - Nature, 2018 - nature.com
Here we analyse genetic variation, population structure and diversity among 3,010 diverse
Asian cultivated rice (Oryza sativa L.) genomes from the 3,000 Rice Genomes Project. Our …

Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine

Y Zhang, X Li, D Zou, W Liu, J Yang… - The Journal of …, 2008 - academic.oup.com
Objective: The objective of the study was to develop clinical practice guidelines for the
diagnosis of Cushing's syndrome. Participants: The Task Force included a chair, selected by …

Role of the unfolded protein response regulator GRP78/BiP in development, cancer, and neurological disorders

M Wang, S Wey, Y Zhang, R Ye… - Antioxidants & redox …, 2009 - liebertpub.com
GRP78/BiP is a major endoplasmic reticulum (ER) chaperone protein critical for protein
quality control of the ER, as well as controlling the activation of the ER-transmembrane …

Intrinsically fluorescent carbon dots with tunable emission derived from hydrothermal treatment of glucose in the presence of monopotassium phosphate

ZC Yang, M Wang, AM Yong, SY Wong… - Chemical …, 2011 - pubs.rsc.org
A facile method is developed to synthesize intrinsically fluorescent carbon dots by
hydrothermal treatment of glucose in the presence of monopotassium phosphate. The …

[HTML][HTML] Prostanoids in health and disease

EM Smyth, T Grosser, M Wang, Y Yu… - Journal of lipid …, 2009 - ASBMB
The prostanoids are a family of lipid mediators generated by the action of cyclooxygenase
on a 20-carbon unsaturated fatty acid, arachidonic acid. Prostanoids are generated widely in …

[HTML][HTML] Gut microbiota influence immunotherapy responses: mechanisms and therapeutic strategies

Y Lu, X Yuan, M Wang, Z He, H Li, J Wang… - Journal of hematology & …, 2022 - Springer
The gut microbiota have long been recognized to play a key role in human health and
disease. Currently, several lines of evidence from preclinical to clinical research have …