Importance Several studies have reported antidepressant effects of anti-inflammatory
treatment; however, the results have been conflicting and detrimental adverse effects may …

Atherosclerosis is the most common cause of chronic arterial occlusive disease of the lower
extremities. The arterial narrowing or obstruction that occurs as a result of the atherosclerotic …

Background Numerous randomised trials have compared coronary artery bypass grafting
(CABG) with percutaneous coronary intervention (PCI) for patients with coronary artery …

Background In some randomized trials comparing revascularization strategies for patients
with diabetes, coronary-artery bypass grafting (CABG) has had a better outcome than …

The management of low-risk patients presenting to emergency departments is a common
and challenging clinical problem entailing 8 million emergency department visits annually …

Background The potential for cyclo-oxygenase 2 (COX2)-selective inhibitors to increase the
risk for myocardial infarction is controversial. The Therapeutic Arthritis Research and …

Background Thromboembolic disease is common in coronavirus disease-2019 (COVID-19).
There is limited evidence on the association of in-hospital anticoagulation (AC) with …

Background Nearly half of patients hospitalized with unstable angina eventually receive a
non–cardiac-related diagnosis, yet 5 percent of patients with myocardial infarction are …

Background Dalcetrapib modulates cholesteryl ester transfer protein (CETP) activity to raise
high-density lipoprotein cholesterol (HDL-C). After the failure of torcetrapib it was unknown if …

Importance Among nontraditional cardiovascular risk factors, recent influenzalike infection is
associated with fatal and nonfatal atherothrombotic events. Objectives To determine if …