The focus of the “2014 AHA/ACC Guideline for the Management of Patients With Valvular
Heart Disease” 9, 10 (2014 VHD guideline) was the diagnosis and management of adult …

Objectives: The aim of the current Valve Academic Research Consortium (VARC)-2 initiative
was to revisit the selection and definitions of transcatheter aortic valve implantation (TAVI) …

The scope of this focused update is limited to addressing recommendations on duration of
dual antiplatelet therapy (DAPT)(aspirin plus a P2Y12 inhibitor) in patients with coronary …

Background The use of transcatheter aortic-valve replacement has been shown to reduce
mortality among high-risk patients with aortic stenosis who are not candidates for surgical …

Background In some randomized trials comparing revascularization strategies for patients
with diabetes, coronary-artery bypass grafting (CABG) has had a better outcome than …

Background Percutaneous coronary intervention (PCI) involving drug-eluting stents is
increasingly used to treat complex coronary artery disease, although coronary-artery bypass …

Background Previous trials have shown that among high-risk patients with aortic stenosis,
survival rates are similar with transcatheter aortic-valve replacement (TAVR) and surgical …

Background Among patients with aortic stenosis who are at intermediate or high risk for
death with surgery, major outcomes are similar with transcatheter aortic-valve replacement …

The recommendations listed in this document are, whenever possible, evidence based. An
extensive evidence review was conducted as the document was compiled through …

Background Among patients with heart failure who have mitral regurgitation due to left
ventricular dysfunction, the prognosis is poor. Transcatheter mitral-valve repair may improve …