Cardiac fibroblasts are the most prevalent cell type in the heart and play a key role in
regulating normal myocardial function and in the adverse myocardial remodeling that occurs …

The importance of cardiac fibroblasts in the regulation of myocardial remodelling following
myocardial infarction (MI) is becoming increasingly recognised. Studies over the last few …

Cardiac fibroblasts (CF) are well-established as key regulators of extracellular matrix (ECM)
turnover in the context of myocardial remodelling and fibrosis. Recently, this cell type has …

Objective In addition to direct effects on myocardial cell function, tumor necrosis factor α
(TNFα) contributes to adverse cardiac remodeling by increasing production of other pro …

Cardiac fibroblasts (CF) play a pivotal role in the repair and remodeling of the heart that
occur following myocardial infarction (MI). The transition through the inflammatory …

Objective: The aim of this study was to determine whether chronic β-adrenergic receptor (β-
AR) stimulation induces proliferation of human cardiac fibroblasts and to investigate the …

The aim of this study was to test the hypothesis that oxidative stress induces apoptosis in the
H9c2 cardiac muscle cell line, and that signaling via mitogen-activated protein kinase …

ABSTRACT Increased matrix metalloproteinase‐9 (MMP‐9) expression is associated with
intimal hyperplasia in saphenous vein (SV) bypass grafts. Recent evidence suggests that …

Piezo1 is a mechanosensitive cation channel with widespread physiological importance;
however, its role in the heart is poorly understood. Cardiac fibroblasts help preserve …

Cardiac myofibroblasts (CMF) play a key role in infarct repair and scar formation following
myocardial infarction (MI) and are also an important source of proinflammatory cytokines …