Optical coherence tomography in coronary atherosclerosis assessment and intervention

M Araki, SJ Park, HL Dauerman, S Uemura… - Nature Reviews …, 2022 - nature.com
Since optical coherence tomography (OCT) was first performed in humans two decades ago,
this imaging modality has been widely adopted in research on coronary atherosclerosis and …

Vulnerable plaques and patients: state-of-the-art

M Tomaniak, Y Katagiri, R Modolo… - European heart …, 2020 - academic.oup.com
Despite advanced understanding of the biology of atherosclerosis, coronary heart disease
remains the leading cause of death worldwide. Progress has been challenging as half of the …

Vascular superoxide production by NAD (P) H oxidase: association with endothelial dysfunction and clinical risk factors

TJ Guzik, NEJ West, E Black, D McDonald… - Circulation …, 2000 - Am Heart Assoc
Superoxide anion plays important roles in vascular disease states. Increased superoxide
production contributes to reduced nitric oxide (NO) bioactivity and endothelial dysfunction in …

Optical coherence tomography–guided versus angiography-guided pci

ZA Ali, U Landmesser, A Maehara… - … England Journal of …, 2023 - Mass Medical Soc
Background Data regarding clinical outcomes after optical coherence tomography (OCT)–
guided percutaneous coronary intervention (PCI) as compared with angiography-guided …

Association between IVUS findings and adverse outcomes in patients with coronary artery disease: the VIVA (VH-IVUS in Vulnerable Atherosclerosis) Study

PA Calvert, DR Obaid, M O'Sullivan, LM Shapiro… - JACC: Cardiovascular …, 2011 - jacc.org
Objectives: The purpose of this study was to determine whether thin-capped fibroatheromata
(TCFA) identified by virtual histology intravascular ultrasound (VH-IVUS) are associated with …

Clinical outcomes of state-of-the-art percutaneous coronary revascularization in patients with de novo three vessel disease: 1-year results of the SYNTAX II study

J Escaned, C Collet, N Ryan… - European heart …, 2017 - academic.oup.com
Aims To investigate if recent technical and procedural developments in percutaneous
coronary intervention (PCI) significantly influence outcomes in appropriately selected …

Nitric oxide modulates superoxide release and peroxynitrite formation in human blood vessels

TJ Guzik, NEJ West, R Pillai, DP Taggart… - …, 2002 - Am Heart Assoc
Nitric oxide and superoxide have important roles as vascular signaling molecules. Nitric
oxide (NO) reacts rapidly with superoxide, producing peroxynitrite. The relative balance …

Functional effect of the C242T polymorphism in the NAD (P) H oxidase p22phox gene on vascular superoxide production in atherosclerosis

TJ Guzik, NEJ West, E Black, D McDonald… - Circulation, 2000 - Am Heart Assoc
Background—Increased superoxide anion production increases oxidative stress and
reduces nitric oxide bioactivity in vascular disease states. NAD (P) H oxidase is an important …

Mitochondrial DNA damage can promote atherosclerosis independently of reactive oxygen species through effects on smooth muscle cells and monocytes and …

E Yu, PA Calvert, JR Mercer, J Harrison, L Baker… - Circulation, 2013 - Am Heart Assoc
Background—Mitochondrial DNA (mtDNA) damage occurs in both circulating cells and the
vessel wall in human atherosclerosis. However, it is unclear whether mtDNA damage …

Clinical and angiographic predictors of restenosis after stent deployment in diabetic patients

NEJ West, PN Ruygrok, CMC Disco, MWI Webster… - Circulation, 2004 - Am Heart Assoc
Background—Restenosis and consequent adverse cardiac events are increased in
diabetics undergoing percutaneous coronary intervention. Use of intracoronary stents may …