Cumulative acute psychosocial stress is thought to promote the development of a range of
disorders which suggests that biomarkers for the physiological response may become …

Accumulation of advanced glycation endproducts (AGE) in the brain is a feature of ageing
and degeneration, especially in Alzheimer's disease (AD). Increased AGE levels explain …

Three neuropathological features attracted the attention of Alzheimer in his examination of
the brain of Auguste Deter: abnormal fibrillary structures, cortical depositions now termed …

The Internet is gaining popularity as a delivery channel in the banking sector. At the same
time, customer needs are changing. A total of 12 Internet banking operations in the UK are …

The analysis of steroid hormones in hair is increasingly used in the field of stress-related
research to obtain a retrospective index of integrated long-term hormone secretion. Here …

Aims To assess tolerability and optimal time point for initiation of sacubitril/valsartan in
patients stabilised after acute heart failure (AHF). Methods and results TRANSITION was a …

Objectives: The aim of this study was to determine whether left ventricular (LV) midwall
fibrosis, detected by midwall hyperenhancement (MWHE) on late gadolinium enhancement …

English In the UK regeneration strategies and patterns of local service provision have
usually been imposed from the top down. Most communities have had little influence over …

Background Myocardial scarring at the LV pacing site leads to incomplete resynchronization
and a suboptimal symptomatic response to CRT. We sought to determine whether the use of …

Previous research examining hypothalamic–pituitary–adrenal (HPA) axis activity in
generalised anxiety disorder (GAD) has suggested a general hypercortisolism. These …