How hypertrophic cardiomyopathy became a contemporary treatable genetic disease with low mortality: shaped by 50 years of clinical research and practice

BJ Maron, EJ Rowin, SA Casey, MS Maron - JAMA cardiology, 2016 - jamanetwork.com
Hypertrophic cardiomyopathy (HCM) is a relatively common genetic heart disease
encumbered throughout much of its almost 60-year history by a large measure of …

[HTML][HTML] Effect of left ventricular outflow tract obstruction on clinical outcome in hypertrophic cardiomyopathy

MS Maron, I Olivotto, S Betocchi… - … England Journal of …, 2003 - Mass Medical Soc
Background The influence of left ventricular outflow tract obstruction on the clinical outcome
of hypertrophic cardiomyopathy remains unresolved. Methods We assessed the effect of …

[HTML][HTML] Efficacy of implantable cardioverter–defibrillators for the prevention of sudden death in patients with hypertrophic cardiomyopathy

BJ Maron, WK Shen, MS Link, AE Epstein… - … England Journal of …, 2000 - Mass Medical Soc
Background Hypertrophic cardiomyopathy is a genetic disease associated with a risk of
ventricular tachyarrhythmias and sudden death, especially in young patients. Methods We …

Epidemiology of hypertrophic cardiomyopathy–related death: revisited in a large non–referral-based patient population

BJ Maron, I Olivotto, P Spirito, SA Casey, P Bellone… - Circulation, 2000 - Am Heart Assoc
Background—Death resulting from hypertrophic cardiomyopathy (HCM), particularly when
sudden, has been reported to be largely confined to young persons. These data emanated …

Impact of atrial fibrillation on the clinical course of hypertrophic cardiomyopathy

I Olivotto, F Cecchi, SA Casey, A Dolara, JH Traverse… - Circulation, 2001 - Am Heart Assoc
Background Clinical impact of atrial fibrillation (AF) in hypertrophic cardiomyopathy (HCM) is
largely unresolved. Thus, we analyzed the prognostic implications of AF in a large …

Clinical course of hypertrophic cardiomyopathy in a regional United States cohort

BJ Maron, SA Casey, LC Poliac, TE Gohman… - Jama, 1999 - jamanetwork.com
ContextHypertrophic cardiomyopathy (HCM) has been regarded as a disease that causes
substantial disability, with annual mortality rates of up to 6%, based largely on reports from …

Utility of cardiac magnetic resonance imaging in the diagnosis of hypertrophic cardiomyopathy

C Rickers, NM Wilke, M Jerosch-Herold, SA Casey… - Circulation, 2005 - Am Heart Assoc
Background—Two-dimensional echocardiography is currently the standard test for the
clinical diagnosis of hypertrophic cardiomyopathy (HCM). The present study was undertaken …

Gender-related differences in the clinical presentation and outcome of hypertrophic cardiomyopathy

I Olivotto, MS Maron, AS Adabag, SA Casey… - Journal of the American …, 2005 - jacc.org
Objectives: The goal of this study was to assess gender-related differences in a multicenter
population with hypertrophic cardiomyopathy (HCM). Background: Little is known regarding …

Assessment of diastolic function with Doppler tissue imaging to predict genotype in preclinical hypertrophic cardiomyopathy

CY Ho, NK Sweitzer, B McDonough, BJ Maron… - Circulation, 2002 - Am Heart Assoc
Background—Unexplained left ventricular hypertrophy (LVH) is considered diagnostic of
hypertrophic cardiomyopathy (HCM) but fails to identify all genetically affected individuals …

Clinical profile of stroke in 900 patients with hypertrophic cardiomyopathy

BJ Maron, I Olivotto, P Bellone, MR Conte… - Journal of the American …, 2002 - jacc.org
Objectives: We sought to assess the occurrence and clinical significance of stroke and
peripheral arterial embolizations at non-central nervous system sites in a large, community …