Introduction Pulmonary vascular dysfunction, pulmonary hypertension (PH), and resulting
right ventricular (RV) failure occur in many critical illnesses and may be associated with a …

Intensive care survivors often experience post-intensive care sequelae, which are frequently
gathered together under the term “post-intensive care syndrome”(PICS). The consequences …

Objective To assess the efficacy and safety of pooled human albumin solutions as part of
fluid volume expansion and resuscitation (with or without improvement of baseline …

Six healthy young male volunteers at a contract research organization were enrolled in the
first phase 1 clinical trial of TGN1412, a novel superagonist anti-CD28 monoclonal antibody …

Utstein-style guidelines contribute to improved public health internationally by providing a
structured framework with which to compare emergency medical services systems …

Background. Morbidity and mortality for critically ill patients with infections remains a global
healthcare problem. We aimed to determine whether β-lactam antibiotic dosing in critically ill …

Naive T cells are stimulated by antigen-presenting dendritic cells (DCs) in secondary
lymphoid organs, but whether other types of cell participate in T cell priming is unclear. Here …

Background Myocardial infarction is a frequent cause of out-of-hospital cardiac arrest.
However, the benefits of early coronary angiography and revascularization in resuscitated …

A review has been undertaken of technologies to remove and recover phosphorus from
wastewater and their potential to facilitate the recycling of phosphorus and its sustainability …

Importance Norepinephrine is currently recommended as the first-line vasopressor in septic
shock; however, early vasopressin use has been proposed as an alternative. Objective To …