Abstract Coronavirus disease-2019 (COVID-19), a viral respiratory illness caused by the
severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), may predispose patients …

determination and the implementation of preventive, diagnostic or therapeutic medical
strategies. However, the ESC Guidelines do not override in any way whatsoever the …

Background—Thrombosis is the common pathology underlying ischemic heart disease,
ischemic stroke, and venous thromboembolism (VTE). The Global Burden of Disease Study …

The task of developing ESC Guidelines covers not only the integration of the most recent
research, but also the creation of educational tools and implementation programmes for the …

Document Reviewers: Jose-Luis Zamorano,(CPG Review Coordinator)(Spain), Felicita
Andreotti (Italy), Michael Ascherman (Czech Republic), George Athanassopoulos (Greece) …

Background The role of fibrinolytic therapy in patients with intermediate-risk pulmonary
embolism is controversial. Methods In a randomized, double-blind trial, we compared …

Objectives. The present study investigated current management strategies as well as the
clinical course of acute major pulmonary embolism. Background. The clinical outcome of …

Background Thrombolytic treatment has been shown to accelerate resolution of major
pulmonary embolism and lead to a rapid improvement of right-side hemodynamics …

Background The use of thrombolytic agents in the treatment of hemodynamically stable
patients with acute submassive pulmonary embolism remains controversial. Methods We …

Obesity is associated with increased cardiovascular morbidity and mortality and with
elevated circulating levels of the satiety factor leptin. This study provides evidence for a …