The tyrosine ZAP‐70 (ζ‐associated protein of 70 kDa) kinase plays a critical role in
activating many downstream signal transduction pathways in T cells following T‐cell …

We have reviewed 31 patients with Takayasu's arteritis followed at two pediatric nephrology
units in Gauteng, South Africa over a 15-year period. There were 25 black patients, 4 white …

To investigate the role of the kinase Zap70 in T cells, we generated mice expressing a
Zap70 mutant whose catalytic activity can be selectively blocked by a small-molecule …

Conductive hydrogels are promising materials with mixed ionic‐electronic conduction to
interface living tissue (ionic signal transmission) with medical devices (electronic signal …

ZAP-70 is a cytoplasmic protein tyrosine kinase that is required for T cell antigen receptor
(TCR) signaling. Both mice and humans deficient in ZAP-70 fail to develop functional T cells …

Background Heart-hand syndromes compose a class of combined congenital cardiac and
limb deformities. The prototypical heart-hand disorder is Holt-Oram syndrome, which is …

A prospective evaluation of emergency portacaval shunt has been conducted during a 12
year period in 138 unselected, consecutive patients with alcoholic cirrhosis and bleeding …

It should be recognized that these guidelines should not be deemed inclusive of all proper
methods of care or exclusive of methods of care reasonably directed to obtaining the same …

The presenting features and treatment responses of six children with junctional ectopic
tachycardia are evaluated. Two of the patients were siblings and both presented in early …

A prospective evaluation of emergency portacaval shunt has been conducted during a ten-
year period in 115 unselected consecutive patients with alcoholic cirrhosis and bleeding …