Empagliflozin treatment is associated with improvements in cardiac energetics and function and reductions in myocardial cellular volume in patients with type 2 …

S Thirunavukarasu, N Jex, A Chowdhary, IU Hassan… - Diabetes, 2021 - Am Diabetes Assoc
Sodium–glucose cotransporter 2 (SGLT2) inhibitors reduce the risk of major adverse
cardiovascular (CV) events and hospitalization for heart failure (HF) in patients with type 2 …

Sex-and age-specific normal values for automated quantitative pixel-wise myocardial perfusion cardiovascular magnetic resonance

LAE Brown, GS Gulsin, SC Onciul… - European Heart …, 2023 - academic.oup.com
Aims Recently developed in-line automated cardiovascular magnetic resonance (CMR)
myocardial perfusion mapping has been shown to be reproducible and comparable with …

Phenotyping hypertrophic cardiomyopathy using cardiac diffusion magnetic resonance imaging: the relationship between microvascular dysfunction and …

A Das, C Kelly, I Teh, C Nguyen… - European Heart …, 2022 - academic.oup.com
Aims Microvascular dysfunction in hypertrophic cardiomyopathy (HCM) is predictive of
clinical decline, however underlying mechanisms remain unclear. Cardiac diffusion tensor …

[HTML][HTML] Cardiovascular magnetic resonance imaging and spectroscopy in clinical long-COVID-19 syndrome: a prospective case–control study

M Gorecka, N Jex, S Thirunavukarasu… - Journal of …, 2022 - Elsevier
Background The underlying pathophysiology of post-coronavirus disease 2019 (long-
COVID-19) syndrome remains unknown, but increased cardiometabolic demand and state …

Maternal cardiac changes in women with obesity and gestational diabetes mellitus

S Thirunavukarasu, F Ansari, R Cubbon… - Diabetes …, 2022 - Am Diabetes Assoc
OBJECTIVE We investigated if women with gestational diabetes mellitus (GDM) in the third
trimester of pregnancy exhibit adverse cardiac alterations in myocardial energetics, function …

Association between type 2 diabetes and changes in myocardial structure, contractile function, Energetics, and blood Flow before and after aortic valve replacement in …

N Jex, JP Greenwood, RM Cubbon, OJ Rider… - Circulation, 2023 - Am Heart Assoc
BACKGROUND: Type 2 diabetes (T2D) is associated with an increased risk of left
ventricular dysfunction after aortic valve replacement (AVR) in patients with severe aortic …

Coronary microvascular function and visceral adiposity in patients with normal body weight and type 2 diabetes

A Chowdhary, S Thirunavukarasu, N Jex, L Coles… - …, 2022 - Wiley Online Library
Objective This study sought to assess whether diabetes affects coronary microvascular
function in individuals with normal body weight. Methods Seventy‐five participants (30 …

Cardiovascular magnetic resonance phenotyping of heart failure with mildly reduced ejection fraction

LAE Brown, A Wahab, E Ikongo… - European Heart …, 2023 - academic.oup.com
Abstract Aims The 2016 European Society of Cardiology Heart Failure Guidelines defined a
new category: heart failure with mid-range ejection fraction (HFmrEF) of 40–49%. This new …

Coexistent diabetes is associated with the presence of adverse phenotypic features in patients with hypertrophic cardiomyopathy

N Jex, A Chowdhary, S Thirunavukarasu… - Diabetes …, 2022 - Am Diabetes Assoc
OBJECTIVE Type 2 diabetes mellitus (T2DM) is associated with worsened clinical outcomes
in hypertrophic cardiomyopathy (HCM) patients. We sought to investigate whether HCM …

Intravascular lithotripsy to treat an underexpanded coronary stent: 4‐Month angiographic and OCT follow‐up

M Alawami, S Thirunavukarasu… - Catheterization and …, 2020 - Wiley Online Library
We report the case of a 79‐year‐old man with stable angina who underwent percutaneous
coronary intervention to a severe and calcified left circumflex lesion. Despite extensive …