Prioritizing candidates of post–myocardial infarction heart failure using plasma proteomics and single-cell transcriptomics

MY Chan, M Efthymios, SH Tan, JW Pickering… - Circulation, 2020 - Am Heart Assoc
Background: Heart failure (HF) is the most common long-term complication of acute
myocardial infarction (MI). Understanding plasma proteins associated with post-MI HF and …

Prognostic value of left atrial strain in aortic stenosis: a competing risk analysis

ESJ Tan, X Jin, YY Oon, SP Chan, L Gong… - Journal of the American …, 2023 - Elsevier
Background The role of left atrial (LA) strain as an imaging biomarker in aortic stenosis is not
well established. The aim of this study was to investigate the prognostic performance of …

[HTML][HTML] Echocardiographic global longitudinal strain is associated with myocardial fibrosis and predicts outcomes in aortic stenosis

TT Le, W Huang, GK Singh, DF Toh, SH Ewe… - Frontiers in …, 2021 - frontiersin.org
Aims: Left ventricular ejection fraction is the conventional measure used to guide heart
failure management, regardless of underlying etiology. Left ventricular global longitudinal …

Prognostic factors after index hospitalization for heart failure with preserved ejection fraction

W Huang, SC Chai, SGS Lee, MR MacDonald… - The American journal of …, 2017 - Elsevier
Heart failure with preserved ejection fraction (HFpEF) has a high clinical burden and
constitutes approximately 20% to 30% of patients with heart failure in Asia. Impaired global …

[HTML][HTML] Treatment of primary aldosteronism and reversal of renin suppression improves left ventricular systolic function

TH Puar, CK Cheong, RSY Foo, SE Saffari… - Frontiers in …, 2022 - frontiersin.org
Introduction Primary aldosteronism (PA) is associated with increased risk of cardiovascular
events. However, treatment of PA has not been shown to improve left ventricular (LV) …

[HTML][HTML] Primary aldosteronism more prevalent in patients with cardioembolic stroke and atrial fibrillation

V Nguyen, TM Tu, MJB Mamauag, J Lai… - Frontiers in …, 2022 - frontiersin.org
Background Primary aldosteronism (PA) is the most common cause of secondary
hypertension, and patients are at an increased risk of atrial fibrillation (AF) and stroke. We …

[HTML][HTML] Improvement in quality of life and psychological symptoms after treatment for primary aldosteronism: Asian Cohort Study

YK Tan, YH Kwan, DCL Teo, M Velema… - Endocrine …, 2021 - ec.bioscientifica.com
Background: In addition to increased cardiovascular risk, patients with primary
aldosteronism (PA) also suffer from impaired health–related quality of life (HRQoL) and …

Novel predictive role for mid-regional proadrenomedullin in moderate to severe aortic stenosis

ESJ Tan, YY Oon, SP Chan, OW Liew, JPC Chong… - Heart, 2022 - heart.bmj.com
Objective We investigated the prognostic significance of selected known and novel
circulating biomarkers in aortic stenosis (AS). Methods N-terminal pro-BNP (NT-proBNP) …

[HTML][HTML] A review of the safety and clinical utility of contrast echocardiography

SC Chai, PJ Tan, KL Tong - Singapore Medical Journal, 2020 - ncbi.nlm.nih.gov
There are limitations to the sensitivity and specificity of conventional two-dimensional
echocardiograms in making an accurate diagnosis in certain patient populations. This led to …

Sex differences in 1-year rehospitalization for heart failure and myocardial infarction after primary percutaneous coronary intervention

H Zheng, LL Foo, HC Tan, AM Richards… - The American Journal of …, 2019 - Elsevier
It is unclear whether universal access to primary percutaneous coronary intervention (pPCI)
may reduce sex differences in 1-year rehospitalization for heart failure (HF) and myocardial …