Despite substantial scientific progress over the past two decades, malaria remains a
worldwide burden that causes hundreds of thousands of deaths every year. New, affordable …

A decade of discovery and development of new anti-malarial medicines has led to a
renewed focus on malaria elimination and eradication. Changes in the way new anti …

Despite being one of the most prevalent tropical diseases, for many years malaria was not a
commercial priority for the pharmaceutical industry. However, in response to the emergence …

During organogenesis, immunosurveillance, and inflammation, chemokines selectively
recruit leukocytes by activating seven-transmembrane-spanning receptors. It has been …

Context High rates of alcohol misuse after deployment have been reported among
personnel returning from past conflicts, yet investigations of alcohol misuse after return from …

Abstract Background and Methods. Patients with Parkinson's disease tend to have a
reduced response to levodopa after 5 to 20 years of therapy, with" on—off" fluctuations …

The chemokine receptors CXCR4 and CCR5 have recently been shown to act as
coreceptors, in concert with CD4, for human immunodeficiency virus–type 1 (HIV-1) …

The complex pathophysiology of lung allergic inflammation and bronchial
hyperresponsiveness (BHR) that characterize asthma is achieved by the regulated …

Several members of the chemokine receptor family have been shown to function in
association with CD4 to permit HIV-1 entry and infection. However, the mechanism by which …

Kaposi's sarcoma–associated herpesvirus encodes a chemokine called vMIP-II. This protein
displayed a broader spectrum of receptor activities than any mammalian chemokine as it …