[HTML][HTML] Consensus guidelines for the definition, detection and interpretation of immunogenic cell death
…, P Vandenabeele, T Yamazaki… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Cells succumbing to stress via regulated cell death (RCD) can initiate an adaptive immune
response associated with immunological memory, provided they display sufficient …
response associated with immunological memory, provided they display sufficient …
[HTML][HTML] Mitochondrial control of inflammation
Numerous mitochondrial constituents and metabolic products can function as damage-
associated molecular patterns (DAMPs) and promote inflammation when released into the …
associated molecular patterns (DAMPs) and promote inflammation when released into the …
A guide to membraneless organelles and their various roles in gene regulation
…, K Ninomiya, S Nakagawa, T Yamazaki - … Reviews Molecular Cell …, 2023 - nature.com
Membraneless organelles (MLOs) are detected in cells as dots of mesoscopic size. By
undergoing phase separation into a liquid-like or gel-like phase, MLOs contribute to …
undergoing phase separation into a liquid-like or gel-like phase, MLOs contribute to …
Pembrolizumab alone or with chemotherapy versus cetuximab with chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck …
…, K Tanaka, T Ueda, H Yamaguchi, T Yamazaki… - The Lancet, 2019 - thelancet.com
Background Pembrolizumab is active in head and neck squamous cell carcinoma (HNSCC),
with programmed cell death ligand 1 (PD-L1) expression associated with improved …
with programmed cell death ligand 1 (PD-L1) expression associated with improved …
Differentiation of mouse myeloid leukemia cells induced by 1 alpha, 25-dihydroxyvitamin D3.
…, M Takeda, K Konno, T Yamazaki… - Proceedings of the …, 1981 - National Acad Sciences
Mouse myeloid leukemia cells can be induced to differentiate into macrophages in vitro by 1
alpha, 25-dihydroxyvitamin D3, the active form of vitamin D3. The minimal concentration of 1 …
alpha, 25-dihydroxyvitamin D3, the active form of vitamin D3. The minimal concentration of 1 …
Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota
Antibodies targeting CTLA-4 have been successfully used as cancer immunotherapy. We
find that the antitumor effects of CTLA-4 blockade depend on distinct Bacteroides species. In …
find that the antitumor effects of CTLA-4 blockade depend on distinct Bacteroides species. In …
Expression of programmed death 1 ligands by murine T cells and APC
T Yamazaki, H Akiba, H Iwai, H Matsuda… - The Journal of …, 2002 - journals.aai.org
Abstract Programmed death 1 (PD-1) is a new member of the CD28/CTLA-4 family, which
has been implicated in the maintenance of peripheral tolerance. Two ligands for PD-1 …
has been implicated in the maintenance of peripheral tolerance. Two ligands for PD-1 …
Zero-and low-field spin relaxation studied by positive muons
…, YJ Uemura, J Imazato, N Nishida, T Yamazaki… - Physical Review B, 1979 - APS
Zero-and low-field spin-relaxation functions have been studied for the first time by using
positive muons, and results are compared with the stochastic theory of low-field relaxation …
positive muons, and results are compared with the stochastic theory of low-field relaxation …
Cancer cell–autonomous contribution of type I interferon signaling to the efficacy of chemotherapy
A Sistigu, T Yamazaki, E Vacchelli, K Chaba, DP Enot… - Nature medicine, 2014 - nature.com
Some of the anti-neoplastic effects of anthracyclines in mice originate from the induction of
innate and T cell–mediated anticancer immune responses. Here we demonstrate that …
innate and T cell–mediated anticancer immune responses. Here we demonstrate that …
The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide
Cyclophosphamide is one of several clinically important cancer drugs whose therapeutic
efficacy is due in part to their ability to stimulate antitumor immune responses. Studying …
efficacy is due in part to their ability to stimulate antitumor immune responses. Studying …