Background The female preponderance in heart failure with preserved ejection fraction
(HFpEF) is a distinguishing feature of this disorder, but the association of sex with degree of …

Background Modification of arrhythmogenic substrates with extensive ablation comprising
linear and/or complex fractional atrial electrogram ablation in addition to pulmonary vein …

* P< 0.001 quencies (VAFs) were significantly higher in cfDNAs than in tdDNAs (mean,
39.8% vs. 2.6%; P< 0.001)(Figure 1C). In 5 patients, 15 variants were called in cfDNAs, but …

The article discusses a study on the link of MYD88 (L265P) mutation to poor prognosis and
high risk of progression in primary central nervous system lymphoma (PCNSL) patients …

Aims Frailty is associated with prognosis of cardiovascular diseases. However, the
significance of frailty in patients with heart failure with preserved ejection fraction (HFpEF) …

Objective Using cluster analysis, to identify the subgroup of patients with APS with the
poorest prognosis and clarify the characteristics of that subgroup. Methods This is a …

Objective Our previously established machine learning-based clustering model classified
heart failure with preserved ejection fraction (HFpEF) into four distinct phenotypes. Given the …

Objectives DNA methyltransferases (DNMTs) are an important part of the methylation
pathway that is highly correlated with the pathophysiology of cancers. Several studies have …

As the use of emergency generators for buildings increases, the near-field dispersion of high-
temperature and high-buoyancy exhaust gas is becoming a concern. We conducted …

Objective The pathophysiological heterogeneity of heart failure with preserved ejection
fraction (HFpEF) makes the conventional 'one-size-fits-all'treatment approach difficult. We …