Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts

Y Shiba, S Fernandes, WZ Zhu, D Filice, V Muskheli… - Nature, 2012 - nature.com
Transplantation studies in mice and rats have shown that human embryonic-stem-cell-
derived cardiomyocytes (hESC-CMs) can improve the function of infarcted hearts,,, but two …

Toward genetics-driven early intervention in dilated cardiomyopathy: design and implementation of the DCM Precision Medicine Study

DD Kinnamon, A Morales, DJ Bowen… - Circulation …, 2017 - Am Heart Assoc
Background—The cause of idiopathic dilated cardiomyopathy (DCM) is unknown by
definition, but its familial subtype is considered to have a genetic component. We …

Challenges facing early career academic cardiologists

CW Tong, T Ahmad, EL Brittain, TJ Bunch… - Journal of the American …, 2014 - jacc.org
Early career academic cardiologists currently face unprecedented challenges that threaten a
highly valued career path. A team consisting of early career professionals and senior …

Left ventricular assist device inflow cannula angle and thrombosis risk

VK Chivukula, JA Beckman, AR Prisco… - Circulation: Heart …, 2018 - Am Heart Assoc
Background: As heart failure prevalence continues to increase in the setting of a static donor
supply, left ventricular assist device (LVAD) therapy for end-stage heart failure continues to …

A novel method to predict the proportional risk of sudden cardiac death in heart failure: derivation of the Seattle Proportional Risk Model

R Shadman, JE Poole, TF Dardas, D Mozaffarian… - Heart Rhythm, 2015 - Elsevier
Background Patients with heart failure are at increased risk of both sudden death and pump
failure death. Strategies to better identify those who have greatest net benefit from …

Impact of center left ventricular assist device volume on outcomes after implantation: an INTERMACS analysis

JA Cowger, JM Stulak, P Shah, TF Dardas… - JACC: Heart Failure, 2017 - jacc.org
Objectives: This study examined patient outcomes after left ventricular assist device (LVAD)
implantation across a range of center surgical volumes. Background: In order for a center to …

Right-sided heart failure: diagnosis and treatment strategies

JC Matthews, TF Dardas, MP Dorsch… - Current treatment options …, 2008 - Springer
Opinion statement Right ventricular (RV) dysfunction in the setting of cardiomyopathy,
ischemia, and pulmonary hypertension is associated with high morbidity and mortality, but …

Transplant registrants with implanted left ventricular assist devices have insufficient risk to justify elective organ procurement and transplantation network status 1A …

T Dardas, NA Mokadam, F Pagani, K Aaronson… - Journal of the American …, 2012 - jacc.org
Objectives: The goal of this research was to identify disparities in risk within heart transplant
urgency designations. Background: Patients with left ventricular assist devices (LVADs) are …

Improved outcomes of heart transplantation in adults with congenital heart disease receiving regionalized care

VP Nguyen, SJ Dolgner, TF Dardas, ED Verrier… - Journal of the American …, 2019 - jacc.org
Background: The number of adult congenital heart disease (CHD) patients undergoing heart
transplantation is increasing rapidly. CHD patients have higher surgical risk at …

Long-term survival on LVAD support: device complications and end-organ dysfunction limit long-term success

IM Hariri, T Dardas, M Kanwar, R Cogswell… - The Journal of Heart and …, 2022 - Elsevier
Background Preoperative variables can predict short term left ventricular assist device
(LVAD) survival, but predictors of extended survival remain insufficiently characterized …